2,6-dibutylbenzaldehyde oxime

Base Information

• Chemical Name: 2,6-dibutylbenzaldehyde oxime
• CAS No.: 1571120-40-5
• Molecular Formula: C₁₅H₂₃NO
• Molecular Weight: 233.354
• Mol file: 1571120-40-5.mol

Synonyms:2,6-dibutylbenzaldehyde oxime

Chemical Property of 2,6-dibutylbenzaldehyde oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-dibutylbenzaldehyde oxime

There total 4 articles about 2,6-dibutylbenzaldehyde oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2,6-Dibutylbenzaldehyde (126278-83-9) → 2,6-dibutylbenzaldehyde oxime (1571120-40-5)

Guidance literature:

With pyridine; hydroxylamine hydrochloride; at 60 ℃; for 1h;

DOI:10.1016/j.bmc.2014.01.037

Reference yield:

2-(2,6-difluorophenyl)-4,5-dihydro-4,4-dimethyl-1,3-oxazole (66464-26-4) → 2,6-dibutylbenzaldehyde oxime (1571120-40-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: tetrahydrofuran / 12 h / Reflux; Inert atmosphere

2.1: lithium in liquid ammonia / tetrahydrofuran

3.1: N-chloro-succinimide / dichloromethane / 20 °C

3.2: basic alumina

4.1: pyridine; hydroxylamine hydrochloride / 1 h / 60 °C

With pyridine; N-chloro-succinimide; hydroxylamine hydrochloride; In tetrahydrofuran; dichloromethane;

DOI:10.1016/j.bmc.2014.01.037

Reference yield:

2-(2,6-dibutylphenyl)-4,5-dihydro-4,4-dimethyl-1,3-oxazole (115890-88-5) → 2,6-dibutylbenzaldehyde oxime (1571120-40-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: lithium in liquid ammonia / tetrahydrofuran

2.1: N-chloro-succinimide / dichloromethane / 20 °C

2.2: basic alumina

3.1: pyridine; hydroxylamine hydrochloride / 1 h / 60 °C

With pyridine; N-chloro-succinimide; hydroxylamine hydrochloride; In tetrahydrofuran; dichloromethane;

DOI:10.1016/j.bmc.2014.01.037

upstream raw materials:

2,6-Dibutylbenzaldehyde

2-(2,6-difluorophenyl)-4,5-dihydro-4,4-dimethyl-1,3-oxazole

2-(2,6-dibutylphenyl)-4,5-dihydro-4,4-dimethyl-1,3-oxazole

2-(2,6-dibutylphenyl)methylamino-2-methyl-1-propanol

Downstream raw materials:

2,6-Dibutylbenzylamine hydrochloride