(4S,1R)-4-[8-{(tert-butyldiphenylsilyl)oxy}octyl]-2-cyclopentenyl acetate

Base Information

Chemical Name:(4S,1R)-4-[8-{(tert-butyldiphenylsilyl)oxy}octyl]-2-cyclopentenyl acetate
CAS No.:470466-98-9
Molecular Formula:C₃₁H₄₄O₃Si
Molecular Weight:492.774
Hs Code.:

Synonyms:(4S,1R)-4-[8-{(tert-butyldiphenylsilyl)oxy}octyl]-2-cyclopentenyl acetate

Suppliers and Price of (4S,1R)-4-[8-{(tert-butyldiphenylsilyl)oxy}octyl]-2-cyclopentenyl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S,1R)-4-[8-{(tert-butyldiphenylsilyl)oxy}octyl]-2-cyclopentenyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S,1R)-4-[8-{(tert-butyldiphenylsilyl)oxy}octyl]-2-cyclopentenyl acetate

There total 3 articles about (4S,1R)-4-[8-{(tert-butyldiphenylsilyl)oxy}octyl]-2-cyclopentenyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 64-19-7,77671-22-8
acetic acid

: 470466-96-7
(4S,1S)-4-[8-{(tert-butyldiphenylsilyl)oxy}octyl]-2-cyclopenten-1-ol

: (4S,1S)-4-[8-{(tert-butyldiphenylsilyl)oxy}octyl]-2-cyclopentenyl acetate

: 470466-98-9
(4S,1R)-4-[8-{(tert-butyldiphenylsilyl)oxy}octyl]-2-cyclopentenyl acetate

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In toluene; at -78 - -60 ℃; for 2h;
DOI:10.1021/jo0348571

Reference yield:

: 60410-16-4
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

: 470466-98-9
(4S,1R)-4-[8-{(tert-butyldiphenylsilyl)oxy}octyl]-2-cyclopentenyl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / CuCN; t-BuMgCl / tetrahydrofuran / 2 h / -18 °C

2: 93 percent / PPh₃; DEAD / toluene / 2 h / -78 - -60 °C

With tert-butylmagnesium chloride; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene; 2: Mitsunobu reaction;
DOI:10.1021/jo0348571

Reference yield:

: (8-(tert-butyldiphenylsilyloxy)octyl)magnesium chloride

: 470466-98-9
(4S,1R)-4-[8-{(tert-butyldiphenylsilyl)oxy}octyl]-2-cyclopentenyl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / CuCN; t-BuMgCl / tetrahydrofuran / 2 h / -18 °C

2: 93 percent / PPh₃; DEAD / toluene / 2 h / -78 - -60 °C

With tert-butylmagnesium chloride; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene; 2: Mitsunobu reaction;
DOI:10.1021/jo0348571