C₄₀H₃₁F₃N₄O₂

Base Information

Chemical Name:C₄₀H₃₁F₃N₄O₂
CAS No.:1620328-25-7
Molecular Formula:C₄₀H₃₁F₃N₄O₂
Molecular Weight:656.707
Hs Code.:

C<sub>40</sub>H<sub>31</sub>F<sub>3</sub>N<sub>4</sub>O<sub>2</sub>

Synonyms:C₄₀H₃₁F₃N₄O₂

Suppliers and Price of C₄₀H₃₁F₃N₄O₂

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₄₀H₃₁F₃N₄O₂

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₄₀H₃₁F₃N₄O₂

There total 10 articles about C₄₀H₃₁F₃N₄O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1160502-31-7
4-iodo-3-(trifluoromethyl)-1-tritylpyrazolo[5,4-b]pyridine

: 1620328-25-7
C₄₀H₃₁F₃N₄O₂

Guidance literature:: Multi-step reaction with 2 steps

1.1: palladium diacetate; 1,4-di(diphenylphosphino)-butane; tert-butylamine; propyl cyanide / water / 16 h / 120 °C

2.1: bis(tri-t-butylphosphine)palladium⁽⁰⁾; N-ethyl-N,N-diisopropylamine / 1,4-dioxane / 0.5 h / 130 °C / Microwave irradiation

2.2: 5 h / 20 °C / 760.05 Torr

With propyl cyanide; bis(tri-t-butylphosphine)palladium⁽⁰⁾; palladium diacetate; tert-butylamine; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane; In 1,4-dioxane; water; 1.1: |Suzuki Coupling / 2.1: |Heck Reaction;
DOI:10.1016/j.bmcl.2014.05.082

Reference yield:

: 1435-51-4
1,3-dibromo-5-fluorobenzene

: 1620328-25-7
C₄₀H₃₁F₃N₄O₂

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium hydride / 1-methyl-pyrrolidin-2-one / 24 h / 120 °C

2.1: lithium chloride / dimethyl sulfoxide; water / 3 h / 165 °C

3.1: tetrabutylammomium bromide; sodium hydroxide / toluene; water / 16 h / 20 °C

4.1: TurboGrignard / tetrahydrofuran / 1.5 h / -20 °C

4.2: 16 h / -20 - 20 °C

5.1: palladium diacetate; 1,4-di(diphenylphosphino)-butane; tert-butylamine; propyl cyanide / water / 16 h / 120 °C

6.1: bis(tri-t-butylphosphine)palladium⁽⁰⁾; N-ethyl-N,N-diisopropylamine / 1,4-dioxane / 0.5 h / 130 °C / Microwave irradiation

6.2: 5 h / 20 °C / 760.05 Torr

With TurboGrignard; propyl cyanide; bis(tri-t-butylphosphine)palladium⁽⁰⁾; tetrabutylammomium bromide; palladium diacetate; sodium hydride; tert-butylamine; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane; lithium chloride; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; 1-methyl-pyrrolidin-2-one; water; dimethyl sulfoxide; toluene; 2.1: |Krapcho Dealkoxycarbonylation / 5.1: |Suzuki Coupling / 6.1: |Heck Reaction;
DOI:10.1016/j.bmcl.2014.05.082

Reference yield:

: cyano-(3,5-dibromophenyl)acetic acid ethyl ester

: 1620328-25-7
C₄₀H₃₁F₃N₄O₂

Guidance literature:: Multi-step reaction with 5 steps

1.1: lithium chloride / dimethyl sulfoxide; water / 3 h / 165 °C

2.1: tetrabutylammomium bromide; sodium hydroxide / toluene; water / 16 h / 20 °C

3.1: TurboGrignard / tetrahydrofuran / 1.5 h / -20 °C

3.2: 16 h / -20 - 20 °C

4.1: palladium diacetate; 1,4-di(diphenylphosphino)-butane; tert-butylamine; propyl cyanide / water / 16 h / 120 °C

5.1: bis(tri-t-butylphosphine)palladium⁽⁰⁾; N-ethyl-N,N-diisopropylamine / 1,4-dioxane / 0.5 h / 130 °C / Microwave irradiation

5.2: 5 h / 20 °C / 760.05 Torr

With TurboGrignard; propyl cyanide; bis(tri-t-butylphosphine)palladium⁽⁰⁾; tetrabutylammomium bromide; palladium diacetate; tert-butylamine; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane; lithium chloride; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; water; dimethyl sulfoxide; toluene; 1.1: |Krapcho Dealkoxycarbonylation / 4.1: |Suzuki Coupling / 5.1: |Heck Reaction;
DOI:10.1016/j.bmcl.2014.05.082