(S)-5-Methoxy-2-aminotetralin

Base Information

• Chemical Name: (S)-5-Methoxy-2-aminotetralin
• CAS No.: 105086-80-4
• Molecular Formula: C₁₁H₁₅NO
• Molecular Weight: 177.246
• Hs Code.: 2922299090
• DSSTox Substance ID: DTXSID90431824
• Wikidata: Q76414617
• Mol file: 105086-80-4.mol

Synonyms:105086-80-4;(S)-5-Methoxy-2-aminotetralin;(S)-(-)-5-METHOXY 2-AMINOTETRALIN;(2S)-5-METHOXY-1,2,3,4-TETRAHYDRONAPHTHALEN-2-AMINE;(S)-5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine;2-Naphthalenamine, 1,2,3,4-tetrahydro-5-methoxy-, (S)-;(S)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine;SCHEMBL895845;(S)-5-methoxy 2-aminotetralin;DTXSID90431824;AKOS017343677;AT27382;PD040914;A18047;EN300-330146;(S)-2-AMINO-5-METHOXYTETRALINHYDROCHLORIDE

Chemical Property of (S)-5-Methoxy-2-aminotetralin

Chemical Property:

• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.548
• Boiling Point: 309.109 °C at 760 mmHg
• PKA: 10.21±0.20(Predicted)
• Flash Point: 147.448 °C
• PSA: 35.25000
• Density: 1.056 g/cm³
• LogP: 2.21150
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 177.115364102
• Heavy Atom Count: 13
• Complexity: 172

Purity/Quality:

97% ^*data from raw suppliers

(S)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC2=C1CCC(C2)N
• Isomeric SMILES: COC1=CC=CC2=C1CC[C@@H](C2)N

Technology Process of (S)-5-Methoxy-2-aminotetralin

There total 18 articles about (S)-5-Methoxy-2-aminotetralin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-acetamido-5-methoxy-1,2,3,4-tetrahydronaphthalene (134865-81-9,153811-23-5,153811-37-1) → 2-Amino-5-methoxy-1,2,3,4-tetrahydronaphthalene (4018-91-1,105086-92-8,105086-80-4)

Guidance literature:

With hydrogenchloride; for 18h; Heating;

DOI:10.1021/jm00122a032

Reference yield: 66.4%

5-methoxy-N-((R)-1-phenylethyl)-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride → 2-Amino-5-methoxy-1,2,3,4-tetrahydronaphthalene (4018-91-1,105086-92-8,105086-80-4)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 60 ℃; for 5h; under 1520.1 - 3800.26 Torr;

Reference yield: 47.0%

2-Amino-5-methoxy-1,2,3,4-tetrahydronaphthalene (4018-91-1,105086-92-8,105086-80-4) → (S)-5-methoxy-2-amino-1,2,3,4-tetrahydronaphthalene (105086-92-8,105086-80-4)

Guidance literature:

With (S)-Mandelic acid; In ethanol; at 40 - 50 ℃; for 2h;

upstream raw materials:

2-(N-benzylamino)-5-methoxytetralin

2-acetamido-5-methoxy-1,2,3,4-tetrahydronaphthalene

5-methoxy-3,4-dihydro-2(1H)-naphthalenone oxime

5-methoxy-2-tetralone

Downstream raw materials:

5,6,7,8-tetrahydro-6-amino-1-naphthol

(S)-5-methoxy-2-amino-1,2,3,4-tetrahydronaphthalene

(S)-N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)propionamide

(S)-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propylamine hydrochloride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 105086-80-4 (S)-2-AMINO-5-METHOXYTETRALIN HYDROCHLORIDE

Send

Send

Metric Ton KG G Pound L ML

Send

Send