3'-deoxy-3'-[2-(5'-deoxythymidin-5'-yl)-2H-tetrazol-5-yl]-5'-O-tritylthymidine

Base Information

Chemical Name:3'-deoxy-3'-[2-(5'-deoxythymidin-5'-yl)-2H-tetrazol-5-yl]-5'-O-tritylthymidine
CAS No.:497068-98-1
Molecular Formula:C₄₀H₄₀N₈O₈
Molecular Weight:760.806
Hs Code.:

Synonyms:3'-deoxy-3'-[2-(5'-deoxythymidin-5'-yl)-2H-tetrazol-5-yl]-5'-O-tritylthymidine

Suppliers and Price of 3'-deoxy-3'-[2-(5'-deoxythymidin-5'-yl)-2H-tetrazol-5-yl]-5'-O-tritylthymidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3'-deoxy-3'-[2-(5'-deoxythymidin-5'-yl)-2H-tetrazol-5-yl]-5'-O-tritylthymidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3'-deoxy-3'-[2-(5'-deoxythymidin-5'-yl)-2H-tetrazol-5-yl]-5'-O-tritylthymidine

There total 2 articles about 3'-deoxy-3'-[2-(5'-deoxythymidin-5'-yl)-2H-tetrazol-5-yl]-5'-O-tritylthymidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 25953-14-4,94892-66-7
1-((2R,4S,5S)-4-hydroxy-5-(iodomethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

: 497068-94-7
3'-deoxy-3'-(1H-terazol-5-yl)-5'-O-tritylthymidine

: 497068-98-1
3'-deoxy-3'-[2-(5'-deoxythymidin-5'-yl)-2H-tetrazol-5-yl]-5'-O-tritylthymidine

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 110 ℃; for 18h;
DOI:10.1002/1522-2675(200209)85:9<2847::AID-HLCA2847>3.0.CO;2-1

Reference yield:

: 118188-69-5
1-(3'-cyano-2',3'-dideoxy-5'-O-trityl-β-D-erythro-pentofuranosyl)thymine

: 497068-98-1
3'-deoxy-3'-[2-(5'-deoxythymidin-5'-yl)-2H-tetrazol-5-yl]-5'-O-tritylthymidine

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / dimethylammonium azide / dimethylformamide / 10 h / 100 °C

2: 89 percent / Et₃N / dimethylformamide / 18 h / 110 °C

With dimethyl ammonium azide; triethylamine; In N,N-dimethyl-formamide;
DOI:10.1002/1522-2675(200209)85:9<2847::AID-HLCA2847>3.0.CO;2-1

Reference yield:

: 497068-98-1
3'-deoxy-3'-[2-(5'-deoxythymidin-5'-yl)-2H-tetrazol-5-yl]-5'-O-tritylthymidine

: 497069-01-9
3'-deoxy-3'-[2-(5'-deoxythymidin-5'-yl)-2H-tetrazol-5-yl]-5'-O-(4,4'-dimethoxytrityl)thymidine

Guidance literature:: Multi-step reaction with 2 steps

1: 20 percent / aq. AcOH / H₂O / 18 h / 80 °C

2: 70 percent / pyridine

With acetic acid; In pyridine; water;
DOI:10.1002/1522-2675(200209)85:9<2847::AID-HLCA2847>3.0.CO;2-1