Technology Process of (E)-N-(3,5-diamino-4-methoxyphenyl)-2-(2,4,6-trimethoxyphenyl)ethenesulfonamide
There total 6 articles about (E)-N-(3,5-diamino-4-methoxyphenyl)-2-(2,4,6-trimethoxyphenyl)ethenesulfonamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium dithionite;
In
water; acetone;
at 50 ℃;
for 0.5h;
Inert atmosphere;
DOI:10.1021/jm400575x
- Guidance literature:
-
Multi-step reaction with 7 steps
1: sulfuric acid; nitric acid / 3 h / 95 °C / Inert atmosphere
2: sulfuric acid; sodium azide / 1,2-dichloro-ethane / 1 h / Reflux; Inert atmosphere
3: potassium hydroxide / 0.5 h / 20 °C / Inert atmosphere
4: triethylamine / dichloromethane / 3 h / 20 °C / Inert atmosphere
5: sodium hydroxide / water / 3 h / 20 °C / Inert atmosphere
6: acetic acid; benzylamine / 8 h / 20 °C / Reflux; Inert atmosphere
7: sodium dithionite / water; acetone / 0.5 h / 50 °C / Inert atmosphere
With
sodium azide; sodium dithionite; sulfuric acid; nitric acid; acetic acid; triethylamine; benzylamine; potassium hydroxide; sodium hydroxide;
In
dichloromethane; water; 1,2-dichloro-ethane; acetone;
DOI:10.1021/jm400575x
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium hydroxide / 0.5 h / 20 °C / Inert atmosphere
2: triethylamine / dichloromethane / 3 h / 20 °C / Inert atmosphere
3: sodium hydroxide / water / 3 h / 20 °C / Inert atmosphere
4: acetic acid; benzylamine / 8 h / 20 °C / Reflux; Inert atmosphere
5: sodium dithionite / water; acetone / 0.5 h / 50 °C / Inert atmosphere
With
sodium dithionite; acetic acid; triethylamine; benzylamine; potassium hydroxide; sodium hydroxide;
In
dichloromethane; water; acetone;
DOI:10.1021/jm400575x
