CAMP SODIUM SALT

Base Information

• Chemical Name: CAMP SODIUM SALT
• CAS No.: 37839-81-9
• Molecular Formula: C10H11N5O6P^.Na
• Molecular Weight: 351.191
• Hs Code.: HOSPHATE, SODIUM SALT PRODUCT IDENTIFICATION
• Mol file: 37839-81-9.mol

Synonyms:3',5'-AMP sodium salt;Cyclic 3',5'-AMP sodium salt;Cyclic 3',5'-adenosine monophosphatemonosodium salt;

Chemical Property of CAMP SODIUM SALT

Chemical Property:

• Appearance/Colour: White crystalline powder
• Melting Point: 219 - 220oC
• Boiling Point: 701.5 °C at 760 mmHg
• Flash Point: 378 °C
• PSA: 167.48000
• LogP: 0.20200
• Storage Temp.: −20°C
• Solubility.: H2O: 50 mg/mL
• Water Solubility.: Soluble in water (50 mg/ml).

Purity/Quality:

97% ^*data from raw suppliers

Adenosine3’,5’-CyclicMonophosphateSodiumSalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Adenosine 3',5'-cyclic monophosphate sodium salt is an Adenosine (A280400) derivative useful as anticancer agent. Adenosine 3?,5?-cyclic monophosphate sodium salt monohydrate is used as an activator of protein kinase A (PKA) . A key regulator of many cellular reactions. Released in response to hormonal stimulation. . Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Acts as a second messenger in signal transduction mechanisms. Promotes apoptosis in resting human B lymphocytes.

Technology Process of CAMP SODIUM SALT

There total 1 articles about CAMP SODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

cAMP (60-92-4) → adenosine 3',5'-(cyclic)phosphate monosodium salt (37839-81-9)

Guidance literature:

With sodium hydroxide; In water; at 40 ℃; for 0.666667h; pH=6.6 - 6.7; Temperature;

Reference yield:

adenosine 3',5'-(cyclic)phosphate monosodium salt (37839-81-9) → 5'-adenosine monophosphate (61-19-8,24937-83-5,67583-85-1)

Guidance literature:

With 1H-imidazole; phosphodiesterase 3',5'-cyclic nucleotide EC 3.1.4.17; magnesium chloride; In phosphate buffer; at 25 ℃; for 0.666667h; pH=7.53; Thermodynamic data;

DOI:10.1016/j.jct.2003.08.002

Reference yield:

[(η6-biphenyl)(ethylenediamine)chlororuthenium(II)] hexafluorophosphate + adenosine 3',5'-(cyclic)phosphate monosodium salt (37839-81-9) → (OPO3CH2C4H4O(OH)C5H2N4(NH2))Ru(H2NCH2CH2NH2)(C6H5C6H5)(1+) + (OPO3CH2C4H4O(OH)C5H2N4(NH2))Ru(H2NCH2CH2NH2)(C6H5C6H5)(1+)

Guidance literature:

With H₂O; In water; 310 K, 3 d; NMR yield of both products was <5%, reaction was monitored by (1)H NMR spectroscopy;

DOI:10.1021/ja027719m

upstream raw materials:

cAMP

Downstream raw materials:

5'-adenosine monophosphate