(E)-4-methyl-N’-(1-(3,4,5-trimethoxyphenyl)ethylidene)benzenesulfonohydrazide

Base Information

• Chemical Name: (E)-4-methyl-N’-(1-(3,4,5-trimethoxyphenyl)ethylidene)benzenesulfonohydrazide
• CAS No.: 1242653-32-2
• Molecular Formula: C₁₈H₂₂N₂O₅S
• Molecular Weight: 378.449
• Mol file: 1242653-32-2.mol

Synonyms:(E)-4-methyl-N’-(1-(3,4,5-trimethoxyphenyl)ethylidene)benzenesulfonohydrazide

Chemical Property of (E)-4-methyl-N’-(1-(3,4,5-trimethoxyphenyl)ethylidene)benzenesulfonohydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-4-methyl-N’-(1-(3,4,5-trimethoxyphenyl)ethylidene)benzenesulfonohydrazide

There total 1 articles about (E)-4-methyl-N’-(1-(3,4,5-trimethoxyphenyl)ethylidene)benzenesulfonohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

methyl (3,4,5-trimethoxyphenyl) ketone (1136-86-3) + toluene-4-sulfonic acid hydrazide (1576-35-8) → (E)-4-methyl-N’-(1-(3,4,5-trimethoxyphenyl)ethylidene)benzenesulfonohydrazide (1242653-32-2)

Guidance literature:

In methanol; at 60 ℃; for 1h; Inert atmosphere;

DOI:10.1021/acs.joc.6b01730

Reference yield: 95.0%

para-iodoanisole (696-62-8) + (E)-4-methyl-N’-(1-(3,4,5-trimethoxyphenyl)ethylidene)benzenesulfonohydrazide (1242653-32-2) → 1,2,3-trimethoxy-5-(1-(4-methoxyphenyl)vinyl)benzene (1067880-32-3)

Guidance literature:

With dichloro bis(acetonitrile) palladium(II); 1,3-bis-(diphenylphosphino)propane; caesium carbonate; In 1,4-dioxane; at 90 ℃; Inert atmosphere;

DOI:10.1021/ol101639g

Reference yield: 82.0%

1-bromo-4-methoxy-benzene (104-92-7) + (E)-4-methyl-N’-(1-(3,4,5-trimethoxyphenyl)ethylidene)benzenesulfonohydrazide (1242653-32-2) → 1,2,3-trimethoxy-5-(1-(4-methoxyphenyl)vinyl)benzene (1067880-32-3)

Guidance literature:

With dichloro bis(acetonitrile) palladium(II); 1,3-bis-(diphenylphosphino)propane; caesium carbonate; In 1,4-dioxane; at 90 ℃; Inert atmosphere;

DOI:10.1021/ol101639g

upstream raw materials:

methyl (3,4,5-trimethoxyphenyl) ketone

toluene-4-sulfonic acid hydrazide

Downstream raw materials:

1,2,3-trimethoxy-5-(1-(4-methoxyphenyl)vinyl)benzene

1-(4'-methoxy-3'-nitrophenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene