Methanesulfonic acid (E)-(1R,2S,5S,10S,11R,14S,15S,16R,17S,18S)-1-hydroxy-10,11-dimethoxy-17-(4-methoxy-benzyloxy)-2,14,16-trimethyl-3-oxo-5-phenyl-4,19-dioxa-bicyclo[13.3.1]nonadec-12-en-18-yl ester

Base Information

Chemical Name:Methanesulfonic acid (E)-(1R,2S,5S,10S,11R,14S,15S,16R,17S,18S)-1-hydroxy-10,11-dimethoxy-17-(4-methoxy-benzyloxy)-2,14,16-trimethyl-3-oxo-5-phenyl-4,19-dioxa-bicyclo[13.3.1]nonadec-12-en-18-yl ester
CAS No.:186768-42-3
Molecular Formula:C₃₇H₅₂O₁₁S
Molecular Weight:704.879
Hs Code.:

Methanesulfonic acid (E)-(1R,2S,5S,10S,11R,14S,15S,16R,17S,18S)-1-hydroxy-10,11-dimethoxy-17-(4-methoxy-benzyloxy)-2,14,16-trimethyl-3-oxo-5-phenyl-4,19-dioxa-bicyclo[13.3.1]nonadec-12-en-18-yl ester

Synonyms:Methanesulfonic acid (E)-(1R,2S,5S,10S,11R,14S,15S,16R,17S,18S)-1-hydroxy-10,11-dimethoxy-17-(4-methoxy-benzyloxy)-2,14,16-trimethyl-3-oxo-5-phenyl-4,19-dioxa-bicyclo[13.3.1]nonadec-12-en-18-yl ester

Suppliers and Price of Methanesulfonic acid (E)-(1R,2S,5S,10S,11R,14S,15S,16R,17S,18S)-1-hydroxy-10,11-dimethoxy-17-(4-methoxy-benzyloxy)-2,14,16-trimethyl-3-oxo-5-phenyl-4,19-dioxa-bicyclo[13.3.1]nonadec-12-en-18-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methanesulfonic acid (E)-(1R,2S,5S,10S,11R,14S,15S,16R,17S,18S)-1-hydroxy-10,11-dimethoxy-17-(4-methoxy-benzyloxy)-2,14,16-trimethyl-3-oxo-5-phenyl-4,19-dioxa-bicyclo[13.3.1]nonadec-12-en-18-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methanesulfonic acid (E)-(1R,2S,5S,10S,11R,14S,15S,16R,17S,18S)-1-hydroxy-10,11-dimethoxy-17-(4-methoxy-benzyloxy)-2,14,16-trimethyl-3-oxo-5-phenyl-4,19-dioxa-bicyclo[13.3.1]nonadec-12-en-18-yl ester

There total 5 articles about Methanesulfonic acid (E)-(1R,2S,5S,10S,11R,14S,15S,16R,17S,18S)-1-hydroxy-10,11-dimethoxy-17-(4-methoxy-benzyloxy)-2,14,16-trimethyl-3-oxo-5-phenyl-4,19-dioxa-bicyclo[13.3.1]nonadec-12-en-18-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 124-63-0
methanesulfonyl chloride

: 186768-35-4
(E)-(1R,2S,5S,10S,11R,14S,15S,16R,17S,18S)-1,18-Dihydroxy-10,11-dimethoxy-17-(4-methoxy-benzyloxy)-2,14,16-trimethyl-5-phenyl-4,19-dioxa-bicyclo[13.3.1]nonadec-12-en-3-one

: 186768-42-3
Methanesulfonic acid (E)-(1R,2S,5S,10S,11R,14S,15S,16R,17S,18S)-1-hydroxy-10,11-dimethoxy-17-(4-methoxy-benzyloxy)-2,14,16-trimethyl-3-oxo-5-phenyl-4,19-dioxa-bicyclo[13.3.1]nonadec-12-en-18-yl ester

Guidance literature:: With triethylamine; In tetrahydrofuran; for 0.333333h; Ambient temperature;
DOI:10.1002/jlac.199719970135

Reference yield:

: 164735-19-7
5-O-(4-methoxybenzyl)soraphen

: 186768-42-3
Methanesulfonic acid (E)-(1R,2S,5S,10S,11R,14S,15S,16R,17S,18S)-1-hydroxy-10,11-dimethoxy-17-(4-methoxy-benzyloxy)-2,14,16-trimethyl-3-oxo-5-phenyl-4,19-dioxa-bicyclo[13.3.1]nonadec-12-en-18-yl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 55 percent / pyridine; SOCl₂ / 0.75 h

2: 71 percent / m-chloroperbenzoic acid, phosphate buffer / tetrahydrofuran / 2 h / Ambient temperature

3: 43 percent / NaBH₄ / tetrahydrofuran; various solvent(s) / 2 h / Ambient temperature

4: 90 percent / 1 M aq. HCl / tetrahydrofuran / Ambient temperature

5: 98 percent / Et₃N / tetrahydrofuran / 0.33 h / Ambient temperature

With pyridine; hydrogenchloride; sodium tetrahydroborate; thionyl chloride; phosphate buffer; triethylamine; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran;
DOI:10.1002/jlac.199719970135

Reference yield:

: 186768-32-1
(E)-(2S,5S,10S,11R,14S,15S,16R,17S)-10,11,18-Trimethoxy-17-(4-methoxy-benzyloxy)-2,14,16-trimethyl-5-phenyl-4,19-dioxa-bicyclo[13.3.1]nonadeca-1⁽¹⁸⁾,12-dien-3-one

: 186768-42-3
Methanesulfonic acid (E)-(1R,2S,5S,10S,11R,14S,15S,16R,17S,18S)-1-hydroxy-10,11-dimethoxy-17-(4-methoxy-benzyloxy)-2,14,16-trimethyl-3-oxo-5-phenyl-4,19-dioxa-bicyclo[13.3.1]nonadec-12-en-18-yl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 71 percent / m-chloroperbenzoic acid, phosphate buffer / tetrahydrofuran / 2 h / Ambient temperature

2: 43 percent / NaBH₄ / tetrahydrofuran; various solvent(s) / 2 h / Ambient temperature

3: 90 percent / 1 M aq. HCl / tetrahydrofuran / Ambient temperature

4: 98 percent / Et₃N / tetrahydrofuran / 0.33 h / Ambient temperature

With hydrogenchloride; sodium tetrahydroborate; phosphate buffer; triethylamine; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran;
DOI:10.1002/jlac.199719970135