1-(4-methylbenzenesulfonyl)-4-(3-fluorobenzene)-1H-1,2,3-triazole

Base Information

• Chemical Name: 1-(4-methylbenzenesulfonyl)-4-(3-fluorobenzene)-1H-1,2,3-triazole
• CAS No.: 1292358-70-3
• Molecular Formula: C₁₅H₁₂FN₃O₂S
• Molecular Weight: 317.344
• Mol file: 1292358-70-3.mol

Synonyms:1-(4-methylbenzenesulfonyl)-4-(3-fluorobenzene)-1H-1,2,3-triazole

Chemical Property of 1-(4-methylbenzenesulfonyl)-4-(3-fluorobenzene)-1H-1,2,3-triazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-methylbenzenesulfonyl)-4-(3-fluorobenzene)-1H-1,2,3-triazole

There total 1 articles about 1-(4-methylbenzenesulfonyl)-4-(3-fluorobenzene)-1H-1,2,3-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4-toluenesulfonyl azide (941-55-9) + 1-ethynyl-3-fluoro-benzene (2561-17-3) → 1-(4-methylbenzenesulfonyl)-4-(3-fluorobenzene)-1H-1,2,3-triazole (1292358-70-3)

Guidance literature:

With (N,N’-bis-{2,6-(di-iso-propyl)phenyl}imidazole-2-ylidene)tri-tert-butylphosphinetetrafluoroborate copper (I); In toluene; at 20 ℃; for 15h;

DOI:10.1021/acs.organomet.7b00506

Reference yield: 95.0%

2-phenylpyridine (1008-89-5) + 1-(4-methylbenzenesulfonyl)-4-(3-fluorobenzene)-1H-1,2,3-triazole (1292358-70-3) → (Z)-(2-(3-fluorophenyl)-2-(2-phenylpyridin-1-ium-1-yl)vinyl)(tosyl)amide

Guidance literature:

With bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; In benzene; at 100 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ja5061609

Reference yield: 92.0%

acetyl phenyl selenide (38447-66-4) + 1-(4-methylbenzenesulfonyl)-4-(3-fluorobenzene)-1H-1,2,3-triazole (1292358-70-3) → (Z)-N-(2-(3-fluorophenyl)-2-(phenylselanyl)vinyl)-N-tosylacetamide

Guidance literature:

With rhodium(II) pivalate; In toluene; at 100 ℃; for 2h; stereoselective reaction; Inert atmosphere;

DOI:10.1002/adsc.202100629

upstream raw materials:

4-toluenesulfonyl azide

1-ethynyl-3-fluoro-benzene

Downstream raw materials:

(Z)-N-(1-(dimethylamino)-3-(3-fluorophenyl)-3-oxo-1-phenylprop-1-en-2-yl)-4-methylbenzenesulfonamide

C₂₄H₂₃FN₂O₃S

3-butyl-4-(3-fluorophenyl)-1-tosyl-1H-pyrrol-2(5H)-one