4-[1-(2-Ethoxy-ethyl)-1H-benzoimidazol-2-ylmethoxy]-benzaldehyde

Base Information

• Chemical Name: 4-[1-(2-Ethoxy-ethyl)-1H-benzoimidazol-2-ylmethoxy]-benzaldehyde
• CAS No.: 198902-26-0
• Molecular Formula: C₁₉H₂₀N₂O₃
• Molecular Weight: 324.379
• Mol file: 198902-26-0.mol

Synonyms:4-[1-(2-Ethoxy-ethyl)-1H-benzoimidazol-2-ylmethoxy]-benzaldehyde

Chemical Property of 4-[1-(2-Ethoxy-ethyl)-1H-benzoimidazol-2-ylmethoxy]-benzaldehyde

Chemical Property:

Purity/Quality:

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Technology Process of 4-[1-(2-Ethoxy-ethyl)-1H-benzoimidazol-2-ylmethoxy]-benzaldehyde

There total 1 articles about 4-[1-(2-Ethoxy-ethyl)-1H-benzoimidazol-2-ylmethoxy]-benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-Chloromethyl-1-(2-ethoxyethyl)-1H-benzimidazole (95893-90-6) + 4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 4-[1-(2-Ethoxy-ethyl)-1H-benzoimidazol-2-ylmethoxy]-benzaldehyde (198902-26-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 90 ℃;

DOI:10.1021/jm960628d

Reference yield: 42.0%

1-[2-hydroxy-5-(1H-tetrazol-5-yl)-phenyl]-ethanone (187273-00-3) + 4-[1-(2-Ethoxy-ethyl)-1H-benzoimidazol-2-ylmethoxy]-benzaldehyde (198902-26-0) → (E)-3-{4-[1-(2-Ethoxy-ethyl)-1H-benzoimidazol-2-ylmethoxy]-phenyl}-1-[2-hydroxy-5-(1H-tetrazol-5-yl)-phenyl]-propenone

Guidance literature:

With potassium hydroxide; In ethanol; for 168h; Ambient temperature;

DOI:10.1021/jm960628d

Reference yield: 38.0%

3-hydroxy-4-(1-oxo-ethane)benzoic acid (102297-62-1) + 4-[1-(2-Ethoxy-ethyl)-1H-benzoimidazol-2-ylmethoxy]-benzaldehyde (198902-26-0) → 4-((E)-3-{4-[1-(2-Ethoxy-ethyl)-1H-benzoimidazol-2-ylmethoxy]-phenyl}-acryloyl)-3-hydroxy-benzoic acid

Guidance literature:

With potassium hydroxide; In ethanol; for 168h; Ambient temperature;

DOI:10.1021/jm960628d

upstream raw materials:

2-Chloromethyl-1-(2-ethoxyethyl)-1H-benzimidazole

4-hydroxy-benzaldehyde