(S)-(+)-2-octyl phenyl sulfide

Base Information

• Chemical Name: (S)-(+)-2-octyl phenyl sulfide
• CAS No.: 111265-18-0
• Molecular Formula: C₁₄H₂₂S
• Molecular Weight: 222.395
• Mol file: 111265-18-0.mol

Synonyms:(S)-(+)-2-octyl phenyl sulfide

Chemical Property of (S)-(+)-2-octyl phenyl sulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of (S)-(+)-2-octyl phenyl sulfide

There total 7 articles about (S)-(+)-2-octyl phenyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

(R)-octan-2-yl methanesulfonate (56772-63-5) + thiophenol (108-98-5) → (S)-(+)-2-octyl phenyl sulfide (111265-18-0)

Guidance literature:

With cesium fluoride; In N,N-dimethyl-formamide; at 50 ℃; for 6h;

DOI:10.1016/S0040-4020(97)00900-9

Reference yield:

(R)-Octan-2-ol (5978-70-1,113301-48-7,4128-32-9) + sodium thiophenolate (930-69-8) → (S)-(+)-2-octyl phenyl sulfide (111265-18-0)

Guidance literature:

Multistep reaction; (i) (tosylation), (ii) /BRN= 3597302/;

DOI:10.1021/ja01478a031

Reference yield:

(S)-(+)-2-bromooctane (1191-24-8) + potassium thiophenolate (3111-52-2) → (S)-(+)-2-octyl phenyl sulfide (111265-18-0) + phenyl 2-octyl sulfide (13921-16-9,78420-38-9,111265-18-0,76003-66-2)

Guidance literature:

2-methylsulfinylpyridine; In toluene; for 36.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1016/S0040-4039(01)82970-1

upstream raw materials:

(R)-Octan-2-ol

sodium thiophenolate

(2R)-2-bromooctane

(S)-(+)-2-bromooctane

Downstream raw materials:

(R)-benzoic acid 1-methylheptyl ester

l-(-)-sec.-Octyl-phenylsulphon

(+)-2-Octyl-phenylsulfon

(-)-2-Octyl-phenylsulfoxid