5-(1,3-dibenzyl-2-oxo-(3ar,6ac)-hexahydro-thieno[3,4-d]imidazol-4-ylidene)-pentanoic acid

Base Information

• Chemical Name: 5-(1,3-dibenzyl-2-oxo-(3ar,6ac)-hexahydro-thieno[3,4-d]imidazol-4-ylidene)-pentanoic acid
• CAS No.: 32692-14-1
• Molecular Formula: C₂₄H₂₆N₂O₃S
• Molecular Weight: 422.548
• Mol file: 32692-14-1.mol

Synonyms:5-(1,3-dibenzyl-2-oxo-(3ar,6ac)-hexahydro-thieno[3,4-d]imidazol-4-ylidene)-pentanoic acid

Chemical Property of 5-(1,3-dibenzyl-2-oxo-(3ar,6ac)-hexahydro-thieno[3,4-d]imidazol-4-ylidene)-pentanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(1,3-dibenzyl-2-oxo-(3ar,6ac)-hexahydro-thieno[3,4-d]imidazol-4-ylidene)-pentanoic acid

There total 2 articles about 5-(1,3-dibenzyl-2-oxo-(3ar,6ac)-hexahydro-thieno[3,4-d]imidazol-4-ylidene)-pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

carbon dioxide (124-38-9,18923-20-1) + (+)-cis-1,3-dibenzyl-hexahydro-1H-thieno[3,4-d]imidazole-2,4-dione (21035-72-3) + 1,4-dichlorobutane (110-56-5) → 5-(1,3-dibenzyl-2-oxo-(3ar,6ac)-hexahydro-thieno[3,4-d]imidazol-4-ylidene)-pentanoic acid (32692-14-1)

Guidance literature:

1,4-dichlorobutane; With magnesium; In tetrahydrofuran; for 0.5h; Inert atmosphere; Sonication;

carbon dioxide; (+)-cis-1,3-dibenzyl-hexahydro-1H-thieno[3,4-d]imidazole-2,4-dione; In tetrahydrofuran; for 1h; under 1500.15 Torr; Inert atmosphere; Sonication;

With sulfuric acid; In tetrahydrofuran; for 0.5h; Solvent; Reagent/catalyst; Inert atmosphere; Sonication;

Reference yield:

→ 5-(1,3-dibenzyl-2-oxo-(3ar,6ac)-hexahydro-thieno[3,4-d]imidazol-4-ylidene)-pentanoic acid (32692-14-1)

Guidance literature:

Hydroxy-dibenzylbiotin VII, AcOH, Δ;

upstream raw materials:

carbon dioxide

(+)-cis-1,3-dibenzyl-hexahydro-1H-thieno[3,4-d]imidazole-2,4-dione

1,4-dichlorobutane