4-<1-(tert-butyldimethylsiloxy)-1-phenylmethyl>-2-thiophenesulfonamide

Base Information

Chemical Name:4-<1-(tert-butyldimethylsiloxy)-1-phenylmethyl>-2-thiophenesulfonamide
CAS No.:155791-21-2
Molecular Formula:C₁₇H₂₅NO₃S₂Si
Molecular Weight:383.608
Hs Code.:

Synonyms:4-<1-(tert-butyldimethylsiloxy)-1-phenylmethyl>-2-thiophenesulfonamide

Suppliers and Price of 4-<1-(tert-butyldimethylsiloxy)-1-phenylmethyl>-2-thiophenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-<1-(tert-butyldimethylsiloxy)-1-phenylmethyl>-2-thiophenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-<1-(tert-butyldimethylsiloxy)-1-phenylmethyl>-2-thiophenesulfonamide

There total 4 articles about 4-<1-(tert-butyldimethylsiloxy)-1-phenylmethyl>-2-thiophenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 498-62-4
3-thiophene carboxaldehyde

: 155791-21-2
4-<1-(tert-butyldimethylsiloxy)-1-phenylmethyl>-2-thiophenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / tetrahydrofuran / 1 h / 0 °C

2: 95 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene / CH₂Cl₂ / 15 h / Ambient temperature

3: 1.) s-BuLi, 2.) SO₂, 3.) NCS

With N-chloro-succinimide; sulfur dioxide; sec.-butyllithium; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm00037a015

Reference yield:

: 102871-39-6
phenyl(thiophen-3-yl)methanol

: 155791-21-2
4-<1-(tert-butyldimethylsiloxy)-1-phenylmethyl>-2-thiophenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene / CH₂Cl₂ / 15 h / Ambient temperature

2: 1.) s-BuLi, 2.) SO₂, 3.) NCS

With N-chloro-succinimide; sulfur dioxide; sec.-butyllithium; 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane;
DOI:10.1021/jm00037a015

Reference yield:

: phenylmagnesium chloride

: 155791-21-2
4-<1-(tert-butyldimethylsiloxy)-1-phenylmethyl>-2-thiophenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / tetrahydrofuran / 1 h / 0 °C

2: 95 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene / CH₂Cl₂ / 15 h / Ambient temperature

3: 1.) s-BuLi, 2.) SO₂, 3.) NCS

With N-chloro-succinimide; sulfur dioxide; sec.-butyllithium; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm00037a015