102871-39-6

Basic information

• Product Name: phenyl(thiophen-3-yl)methanol
• Synonyms: phenyl(thiophen-3-yl)methanol
• CAS NO: 102871-39-6
• Molecular Weight: 190.266
• Mol File: 102871-39-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: phenyl(thiophen-3-yl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: phenyl(thiophen-3-yl)methanol(102871-39-6)
• EPA Substance Registry System: phenyl(thiophen-3-yl)methanol(102871-39-6)

Safety Data

• Hazardous Substances Data: 102871-39-6(Hazardous Substances Data)

Upstream product

• 1192-06-9 3-thienyl lithium 
• 100-52-7 benzaldehyde 
• 498-62-4 3-thiophene carboxaldehyde 
• 10486-61-0 3-thienyl iodide 
• 100-58-3 phenylmagnesium bromide 
• 872-31-1 3-Bromothiophene 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 98-80-6 phenylboronic acid 

Downstream Products

• 6453-99-2 3-benzoylthiophene 
• 185329-74-2 phenyl(thiophen-3-yl)methyl acetate 
• 155791-21-2 4-<1-(tert-butyldimethylsiloxy)-1-phenylmethyl>-2-thiophenesulfonamide 
• 155791-24-5 4-(1-hydroxy-1-phenylmethyl)-2-thiophenesulfonamide 
• 27921-48-8 3-benzylthiophene 
• 101445-57-2 phenyl-[3]thienyl ketone-(2,4-dinitro-phenylhydrazone) 
• 155791-18-7 3-<1-(tert-butyldimethylsiloxy)-1-phenylmethyl>thiophene 

Relevant articles and documents

A LiCl-mediated Br/Mg exchange reaction for the preparation of functionalized aryl- and heteroarylmagnesium compounds from organic bromides

A wide range of aryl and heteroaryl bromides, which are usually sluggish in exchange reactions, are readily converted into the corresponding Grignard reagents by means of a Br/Mg exchange reaction triggered by iPrMgCl·LiCl (see scheme). These Grignard intermediates react with electrophiles in good yields.

Preparation of 3-Thienylzinc and -magnesium Halide via Oxidative Addition of Active Zinc and Magnesium to 3-Iodothiophene

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Employing Arynes for the Generation of Aryl Anion Equivalents and Subsequent Reaction with Aldehydes

Arynes are highly reactive intermediates, which are utilized for the electrophilic arylation of various X-H bonds (X = O, N, S etc.). Herein, a new synthetic strategy is demonstrated, where arynes are converted into aryl anion equivalents by treatment with phosphines and a base. The addition of phosphines to arynes form the phosphonium salts, which in the presence of a carbonate base generates the aryl anion equivalent. Subsequent addition of the aryl anions with aldehydes afforded the secondary alcohols.

An unusual chemoselective oxidation strategy by an unprecedented exploration of an electrophilic center of DMSO: A new facet to classical DMSO oxidation

A conceptually new dimethyl sulfoxide (DMSO) based oxidation process without the use of any activator has been demonstrated for the oxidation of active methylenes and benzhydrols. The developed protocol utilizes the electrophilic center of DMSO for oxidation, which was unexplored before. Mechanistic investigation has confirmed that the source of oxygen is DMSO.