tert-butyl cis-1-((6-bromopyridin-2-yl)methyl)-4-((tert-butyl(diphenyl)silyl)oxy)cyclohexanecarboxylate

Base Information

• Chemical Name: tert-butyl cis-1-((6-bromopyridin-2-yl)methyl)-4-((tert-butyl(diphenyl)silyl)oxy)cyclohexanecarboxylate
• CAS No.: 1010086-53-9
• Molecular Formula: C₃₃H₄₂BrNO₃Si
• Molecular Weight: 608.691
• Mol file: 1010086-53-9.mol

Synonyms:tert-butyl cis-1-((6-bromopyridin-2-yl)methyl)-4-((tert-butyl(diphenyl)silyl)oxy)cyclohexanecarboxylate

Chemical Property of tert-butyl cis-1-((6-bromopyridin-2-yl)methyl)-4-((tert-butyl(diphenyl)silyl)oxy)cyclohexanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl cis-1-((6-bromopyridin-2-yl)methyl)-4-((tert-butyl(diphenyl)silyl)oxy)cyclohexanecarboxylate

There total 1 articles about tert-butyl cis-1-((6-bromopyridin-2-yl)methyl)-4-((tert-butyl(diphenyl)silyl)oxy)cyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-6-bromomethylpyridine (83004-10-8) → tert-butyl cis-1-((6-bromopyridin-2-yl)methyl)-4-((tert-butyl(diphenyl)silyl)oxy)cyclohexanecarboxylate (1010086-53-9)

Guidance literature:

tert-butyl 4-((tert-butyl(diphenyl)silyl)oxy)cyclohexanecarboxylate; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 - 0 ℃; for 1.5h;

2-bromo-6-bromomethylpyridine; With N,N,N,N,N,N-hexamethylphosphoric triamide; In tetrahydrofuran; hexane; at 20 ℃;

Reference yield:

tert-butyl cis-1-((6-bromopyridin-2-yl)methyl)-4-((tert-butyl(diphenyl)silyl)oxy)cyclohexanecarboxylate (1010086-53-9) → tert-butyl cis-1-((6-bromopyridin-2-yl)methyl)-4-hydroxycyclohexanecarboxylate (1010086-55-1)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 - 60 ℃;

upstream raw materials:

2-bromo-6-bromomethylpyridine

Downstream raw materials:

tert-butyl cis-1-((6-bromopyridin-2-yl)methyl)-4-hydroxycyclohexanecarboxylate