2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylpropionamide

Base Information

Chemical Name:2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylpropionamide
CAS No.:745051-32-5
Molecular Formula:C₁₈H₂₂N₂O₄S₂
Molecular Weight:394.516
Hs Code.:

Synonyms:2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylpropionamide

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Chemical Property of 2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylpropionamide

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Technology Process of 2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylpropionamide

There total 2 articles about 2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylpropionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 96-50-4
2-thiazolylamine

: 2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)propionic acid

: 745051-32-5
2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylpropionamide

Guidance literature:: 2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)propionic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; for 0.25h;

2-thiazolylamine; In N,N-dimethyl-formamide; at 20 ℃; for 16h;
DOI:10.1021/jm8003202

Reference yield:

: 96-50-4
2-thiazolylamine

: 745051-32-5
2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylpropionamide

Guidance literature:: 2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)propionic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In DMF (N,N-dimethyl-formamide); for 0.25h;

2-thiazolylamine; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 16h;