4-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-guanidino-N^α-benzyloxycarbonyl-L-cis-proline

Base Information

• Chemical Name: 4-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-guanidino-N^α-benzyloxycarbonyl-L-cis-proline
• CAS No.: 281666-47-5
• Molecular Formula: C₂₈H₃₆N₄O₇S
• Molecular Weight: 572.682

Synonyms:4-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-guanidino-N^α-benzyloxycarbonyl-L-cis-proline

Chemical Property of 4-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-guanidino-N^α-benzyloxycarbonyl-L-cis-proline

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Technology Process of 4-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-guanidino-N^α-benzyloxycarbonyl-L-cis-proline

There total 1 articles about 4-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-guanidino-N^α-benzyloxycarbonyl-L-cis-proline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

2,2,5,7,8-pentamethylchroman-6-sulfonyl chloride (112160-39-1) + 4-guanidino-Nα-benzyloxycarbonyl-L-cis-proline → 4-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-guanidino-Nα-benzyloxycarbonyl-L-cis-proline (281666-47-5)

Guidance literature:

With sodium hydroxide; In acetone; at 0 - 20 ℃; for 4h;

DOI:10.1016/S0040-4020(00)00123-X

upstream raw materials:

2,2,5,7,8-pentamethylchroman-6-sulfonyl chloride

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