112160-39-1

Basic information

• Product Name: 2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULFONYL CHLORIDE
• Synonyms: PMC-CHLORIDE;PMC-CL;2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULFONYL CHLORIDE;2,2,5,7 8-PENTAMETHYLCHROMAN-6-SULPHONYL CHLORIDE;2,2,5,7,8-PENTAMETHYL-CHROMANE-6-SULFONYL CHLORIDE;2,2,5,7,8-PENTAMETHYLCHROMANE-6-SULFONYL;3,4-dihydro-2,2,5,7,8-pentamethyl-2h-1-benzopyran-6-sulfonyl chloride;2,2,5,7,8-pentamethyl-6-chromansulfonyl chloride
• CAS NO: 112160-39-1
• Molecular Formula: C₁₄H₁₉ClO₃S
• Molecular Weight: 302.82
• Mol File: 112160-39-1.mol

Chemical Properties

• Melting Point: 77-82 °C
• Boiling Point: 410.9 °C at 760 mmHg
• Flash Point: 202.3 °C
• Appearance: /
• Density: 1.205 g/cm³
• Vapor Pressure: 1.39E-06mmHg at 25°C
• Refractive Index: 1.526
• Storage Temp.: −20°C
• BRN: 4488701
• CAS DataBase Reference: 2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULFONYL CHLORIDE(112160-39-1)
• EPA Substance Registry System: 2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULFONYL CHLORIDE(112160-39-1)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 112160-39-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2,2,5,7,8-Pentamethylchroman-6-sulfonyl chloride is used as a reagent in organic synthesis for the preparation of various other organic compounds. Its sulfonyl chloride group makes it a valuable tool in the formation of carbon-carbon and carbon-heteroatom bonds, contributing to the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,2,5,7,8-Pentamethylchroman-6-sulfonyl chloride is used as a key intermediate in the synthesis of various pharmaceuticals. Its antioxidant properties and reactivity in organic synthesis make it a useful building block for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
2,2,5,7,8-Pentamethylchroman-6-sulfonyl chloride is also used in the agrochemical industry as a precursor for the synthesis of various agrochemicals. Its versatility in organic synthesis allows for the development of new compounds with potential applications in crop protection and other agricultural areas.
Used in Specialty Chemicals Production:
2,2,5,7,8-Pentamethylchroman-6-sulfonyl chloride is used as a reagent in the production of specialty chemicals. Its unique properties and reactivity make it a valuable component in the synthesis of high-value specialty chemicals for various applications, including materials science, coatings, and other industrial processes.

InChI:InChI=1/C14H19ClO3S/c1-8-9(2)13(19(15,16)17)10(3)11-6-7-14(4,5)18-12(8)11/h6-7H2,1-5H3

Upstream product

• 78-79-5 isoprene 
• 697-82-5 2,3,5-trimethylphenol 
• 55646-01-0 2,2,5,7,8-pentamethyl-chromane 

Downstream Products

• 112160-32-4 N_α-benzyloxycarbonyl-N_G-(2,2,5,7,8-pentamethylchroman-6-sulphonyl)-L-arginine 
• 1246617-26-4 C₄₃H₆₄N₂O₁₁S 
• 1246617-30-0 C₆₅H₉₇N₃O₁₆S₂ 
• 137043-71-1 N^α-<2,2-bis(4'-nitrophenyl)ethoxycarbonyl>-N^G-(2,2,5,7,8-pentamethylchroman-6-sulphonyl)arginine 
• 137043-73-3 N^G-(2,2,5,7,8-pentamethylchroman-6-sulphonyl)-arginylglycylglycine methyl ester tosylate 
• 137043-77-7 N^G-(2,2,5,7,8-pentamethylchroman-6-sulphonyl)-arginylleucinyl-N^G-(2,2,5,7,8-pentamethylchroman-6-sulphonyl)-arginylglycylglycine methyl ester tosylate 
• 112160-37-9 N^G-2,2,5,7,8-pentamethylchroman-6-sulfonyl-L-arginine 
• 112160-36-8 N^α-benzyloxycarbonyl-N^G-(2,2,5,7,8-pentamethylchroman-6-sulphonyl)-arginylglycylglycine methyl ester 
• 119831-72-0 Fmoc-Arg(Pbf)-OH 
• 112160-34-6 N^α-benzyloxycarbonyl-N^G-(2,2,5,7,8-pentamethylchroman-6-sulphonyl)-arginylleucinyl-N^G-(2,2,5,7,8-pentamethylchroman-6 sulphonyl)-arginylglycylglycine methyl ester 
• 161357-49-9 2,2,5,7,8-Pentamethyl-chroman-6-sulfonic acid [(S)-1-(3-cyano-benzyl)-2-(4-methanesulfonyl-piperazin-1-yl)-2-oxo-ethyl]-amide 
• 1026547-34-1 (S)-3-(3-Cyano-phenyl)-2-(2,2,5,7,8-pentamethyl-chroman-6-sulfonylamino)-propionic acid 
• 161357-50-2 3-[(S)-3-(4-Methanesulfonyl-piperazin-1-yl)-3-oxo-2-(2,2,5,7,8-pentamethyl-chroman-6-sulfonylamino)-propyl]-thiobenzamide 

Relevant articles and documents

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