(E)-ethyl 1-<(tert-butoxycarbonyl)amino>-3-<(benzyloxy)amino>cyclobutane-1-carboxylate

Base Information

• Chemical Name: (E)-ethyl 1-<(tert-butoxycarbonyl)amino>-3-<(benzyloxy)amino>cyclobutane-1-carboxylate
• CAS No.: 227453-80-7
• Molecular Formula: C₁₉H₂₈N₂O₅
• Molecular Weight: 364.442
• Mol file: 227453-80-7.mol

Synonyms:(E)-ethyl 1-<(tert-butoxycarbonyl)amino>-3-<(benzyloxy)amino>cyclobutane-1-carboxylate

Chemical Property of (E)-ethyl 1-<(tert-butoxycarbonyl)amino>-3-<(benzyloxy)amino>cyclobutane-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (E)-ethyl 1-<(tert-butoxycarbonyl)amino>-3-<(benzyloxy)amino>cyclobutane-1-carboxylate

There total 1 articles about (E)-ethyl 1-<(tert-butoxycarbonyl)amino>-3-<(benzyloxy)amino>cyclobutane-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-benzyloxyamine (622-33-3) + ethyl 1-<<(tert-butyloxy)carbonyl>amino>-3-oxocyclobutane-1-carboxylate (129287-91-8) → (Z)-ethyl 1-<(tert-butoxycarbonyl)amino>-3-<(benzyloxy)amino>cyclobutane-1-carboxylate (227453-79-4) + (E)-ethyl 1-<(tert-butoxycarbonyl)amino>-3-<(benzyloxy)amino>cyclobutane-1-carboxylate (227453-80-7)

Guidance literature:

With hydrogenchloride; sodium cyanoborohydride; In methanol; for 48h; Yield given; Yields of byproduct given; Ambient temperature;

DOI:10.1021/jm9806897

Reference yield: 100.0%

ethoxycarbonylisocyanate (19617-43-7) + (E)-ethyl 1-<(tert-butoxycarbonyl)amino>-3-<(benzyloxy)amino>cyclobutane-1-carboxylate (227453-80-7) → (E)-ethyl 1-<(tert-butoxycarbonyl)amino>-3-cyclobutane-1-carboxylate (227453-82-9)

Guidance literature:

In tetrahydrofuran; for 0.25h;

DOI:10.1021/jm9806897

upstream raw materials:

N-benzyloxyamine

ethyl 1-<<(tert-butyloxy)carbonyl>amino>-3-oxocyclobutane-1-carboxylate

Downstream raw materials:

(E)-ethyl 1-<(tert-butoxycarbonyl)amino>-3-cyclobutane-1-carboxylate