2-(1-(4-methoxyphenyl)ethoxy)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

• Chemical Name: 2-(1-(4-methoxyphenyl)ethoxy)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS No.: 1566593-64-3
• Molecular Formula: C₁₅H₂₃BO₄
• Molecular Weight: 278.156
• Mol file: 1566593-64-3.mol

Synonyms:2-(1-(4-methoxyphenyl)ethoxy)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property of 2-(1-(4-methoxyphenyl)ethoxy)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 2-(1-(4-methoxyphenyl)ethoxy)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 2 articles about 2-(1-(4-methoxyphenyl)ethoxy)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-(4-methoxyphenyl)ethanone (100-06-1) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 2-(1-(4-methoxyphenyl)ethoxy)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1566593-64-3)

Guidance literature:

With sodium triethylborohydride; In hexane; at 23 ℃; for 24h; Inert atmosphere; Glovebox;

DOI:10.1021/jacs.6b00849

Reference yield: 85.0%

1-(4-methoxyphenyl)ethanone (100-06-1) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → rac-1-(4-methoxyphenyl)-ethanol (3319-15-1) + 2-(1-(4-methoxyphenyl)ethoxy)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1566593-64-3)

Guidance literature:

With tris(cyclopentadienyl)lanthanum(III); In tetrahydrofuran; at 25 ℃; for 1h; Inert atmosphere; Schlenk technique; Glovebox;

DOI:10.1021/acs.orglett.7b01335

Reference yield: 99.0%

2-(1-(4-methoxyphenyl)ethoxy)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1566593-64-3) → rac-1-(4-methoxyphenyl)-ethanol (3319-15-1)

Guidance literature:

With silica gel; In hexane; ethyl acetate;

DOI:10.1002/anie.201607579

upstream raw materials:

1-(4-methoxyphenyl)ethanone

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

Downstream raw materials:

rac-1-(4-methoxyphenyl)-ethanol