(E)-N-3-(IODOPROP-2-ENYL)2E-CARBOXY-3E-(P-TOLYL)-NORTROPAN

Base Information

Chemical Name:(E)-N-3-(IODOPROP-2-ENYL)2E-CARBOXY-3E-(P-TOLYL)-NORTROPAN
CAS No.:311351-26-5
Molecular Formula:C18H22 I N O2
Molecular Weight:411.28
Hs Code.:
Mol file:311351-26-5.mol

Synonyms:8-Azabicyclo[3.2.1]octane-2-carboxylicacid, 8-[(2E)-3-iodo-2-propenyl]-3-(4-methylphenyl)-, (1R,2S,3S,5S)- (9CI);Nor-PE 2I

Suppliers and Price of (E)-N-3-(IODOPROP-2-ENYL)2E-CARBOXY-3E-(P-TOLYL)-NORTROPAN

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Nor-PE2I
1mg
$ 220.00

TRC
Nor-PE2I
10mg
$ 1650.00

TRC
Nor-PE2I
5mg
$ 935.00

American Custom Chemicals Corporation
(E)-N-3-(IODOPROP-2-ENYL)2E-CARBOXY-3E-(PARA-TOLYL)NORTROPAN 95.00%
5MG
$ 502.58

Total 2 raw suppliers

Chemical Property of (E)-N-3-(IODOPROP-2-ENYL)2E-CARBOXY-3E-(P-TOLYL)-NORTROPAN

Chemical Property:

Boiling Point:501.7±50.0 °C(Predicted)
PKA:3.68±0.40(Predicted)
PSA：40.54000
Density:1.505±0.06 g/cm3(Predicted)
LogP:3.90270
Storage Temp.:-20°C Freezer
Solubility.:Dichloromethane; Alcohol

Purity/Quality:: Nor-PE2I ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Nor-PE 2I is an intermediate in the synthesis of Fluoroethyl-PE2I (F591758), which is a useful intermediate that is often used in the synthesis of PET ligands that are used for dopamine transporter imaging.

Technology Process of (E)-N-3-(IODOPROP-2-ENYL)2E-CARBOXY-3E-(P-TOLYL)-NORTROPAN

There total 1 articles about (E)-N-3-(IODOPROP-2-ENYL)2E-CARBOXY-3E-(P-TOLYL)-NORTROPAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: PE2I

: 311351-26-5
C₁₈H₂₂INO₂

Guidance literature:: In 1,4-dioxane; water; Reflux;
DOI:10.1002/jlcr.2927

Reference yield: 54.0%

: 311351-26-5
C₁₈H₂₂INO₂

: 6315-52-2
1,2-bis-tosyloxyethane

: 1391711-43-5
2-(tosyloxy)ethyl 8-[(2E)-3-iodoprop-2-en-1-yl]-3-(4-methyl-phenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate

Guidance literature:: C₁₈H₂₂INO₂; With tetra(n-butyl)ammonium hydroxide; In water; toluene; at 20 ℃; for 0.166667h;

1,2-bis-tosyloxyethane; In acetonitrile; at 20 ℃; for 2h;
DOI:10.1002/jlcr.2927

Reference yield: 54.0%

: 311351-26-5
C₁₈H₂₂INO₂

: 383-50-6
2-fluoroethyl tosylate

: 949091-68-3
FE-PE₂I

Guidance literature:: C₁₈H₂₂INO₂; With tetra(n-butyl)ammonium hydroxide; In water; toluene; at 20 ℃; for 0.166667h;

2-fluoroethyl tosylate; In N,N-dimethyl-formamide; at 70 ℃; for 1h;
DOI:10.1002/jlcr.2927