tert-Butyl (3-iodophenyl)carbamate

Base Information

Chemical Name:tert-Butyl (3-iodophenyl)carbamate
CAS No.:143390-49-2
Molecular Formula:C11H14 I N O2
Molecular Weight:319.142
Hs Code.:2924299090
European Community (EC) Number:802-983-9
DSSTox Substance ID:DTXSID90514489
Nikkaji Number:J1.902.304D
Wikidata:Q82374850
Mol file:143390-49-2.mol

Synonyms:143390-49-2;tert-Butyl (3-iodophenyl)carbamate;(3-IODO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER;N-Boc-3-iodoaniline;TERT-BUTYL N-(3-IODOPHENYL)CARBAMATE;N-(3-Iodophenyl)-1,1-dimethylethyl Ester Carbamic Acid;N-BOC 3-IODOANILINE;MFCD08703142;N-Boc-3-iodoaniline, 97%;SCHEMBL711197;tert-butyl 3-iodophenylcarbamate;Carbamic acid, (3-iodophenyl)-, 1,1-dimethylethyl ester;DTXSID90514489;MPCQRNOVFYBCTQ-UHFFFAOYSA-N;tert-Butyl(3-iodophenyl)carbamate;AKOS010055003;CS-W009902;MB06550;BS-25282;SY041756;iodo-3-(tert-butyloxycarbonyl)aminobenzene;FT-0670385;D85817;EN300-3580249;(3-IODO-PHENYL)-CARBAMICACIDTERT-BUTYLESTER;J-007805

Suppliers and Price of tert-Butyl (3-iodophenyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(3-Iodophenyl)-1,1-dimethylethylEsterCarbamicAcid
25mg
$ 70.00

Sigma-Aldrich
N-Boc-3-iodoaniline 97%
1g
$ 48.20

Crysdot
tert-Butyl(3-iodophenyl)carbamate 95+%
25g
$ 485.00

Chemenu
tert-Butyl(3-iodophenyl)carbamate 95%
25g
$ 458.00

American Custom Chemicals Corporation
(3-IODO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER 95.00%
5MG
$ 503.00

AK Scientific
N-Boc-3-iodoaniline
1g
$ 111.00

Acrotein
N-Boc3-iodoaniline 97%
1g
$ 45.83

Total 36 raw suppliers

Chemical Property of tert-Butyl (3-iodophenyl)carbamate

Chemical Property:

Melting Point:71-75°C
Boiling Point:434.1 °C at 760 mmHg
PKA:13.30±0.70(Predicted)
Flash Point:216.3 °C
PSA：38.33000
Density:1.601 g/cm³
LogP:3.71120
Solubility.:Dichloromethane, Ethyl Acetate
XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:319.00693
Heavy Atom Count:15
Complexity:225

Purity/Quality:

99%, ^*data from raw suppliers

N-(3-Iodophenyl)-1,1-dimethylethylEsterCarbamicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,N
Hazard Codes:Xn,N
Statements: 22-43-50
Safety Statements: 36/37-61

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CC(=CC=C1)I
Uses N-(3-Iodophenyl)-1,1-dimethylethyl Ester Carbamic Acid (cas# 143390-49-2) is a compound useful in organic synthesis.

Technology Process of tert-Butyl (3-iodophenyl)carbamate

There total 1 articles about tert-Butyl (3-iodophenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 626-01-7
3-Iodoaniline

: 143390-49-2
iodo-3-(tert-butyloxycarbonylamino)benzene

Guidance literature:: In neat (no solvent); at 80 ℃; for 0.166667h; chemoselective reaction; Green chemistry;
DOI:10.1007/s11164-016-2702-9

Reference yield: 92.0%

: 143390-49-2
iodo-3-(tert-butyloxycarbonylamino)benzene

: 1066-54-2
trimethylsilylacetylene

: tert-butyl (3-((trimethylsilyl)ethynyl)phenyl)carbamate

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; at 50 ℃; for 2h;
DOI:10.1016/S0040-4020(98)00536-5

Reference yield: 92.0%

: 1809-20-7
diisopropyl hydrogenphosphonate

: 143390-49-2
iodo-3-(tert-butyloxycarbonylamino)benzene

: 1073561-77-9
diisopropyl (3-tert-butoxycarbonylamino-phenyl)-phosphonate

Guidance literature:: With 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 110 ℃; for 24h;
DOI:10.1016/j.jorganchem.2008.07.020