3-(5-Bromothiazol-2-yloxy)phenol

Base Information

Chemical Name:3-(5-Bromothiazol-2-yloxy)phenol
CAS No.:904961-08-6
Molecular Formula:C9H6 Br N O2 S
Molecular Weight:272.122
Hs Code.:2934100090
DSSTox Substance ID:DTXSID20698847
Wikidata:Q72512923
Mol file:904961-08-6.mol

Synonyms:3-(5-BROMOTHIAZOL-2-YLOXY)PHENOL;904961-08-6;3-((5-Bromothiazol-2-yl)oxy)phenol;3-[(5-BROMO-1,3-THIAZOL-2-YL)OXY]PHENOL;AMY4739;DTXSID20698847;MFCD08752640;AKOS027380135;BS-24836;PHENOL,3-[(5-BROMO-2-THIAZOLYL)OXY]-

Suppliers and Price of 3-(5-Bromothiazol-2-yloxy)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-((5-Bromothiazol-2-yl)oxy)phenol 97%
5g
$ 706.00

American Custom Chemicals Corporation
3-(5-BROMOTHIAZOL-2-YLOXY)PHENOL 95.00%
5MG
$ 504.72

Total 4 raw suppliers

Chemical Property of 3-(5-Bromothiazol-2-yloxy)phenol

Chemical Property:

Boiling Point:379.5 °C at 760 mmHg
Flash Point:183.3 °C
PSA：70.59000
Density:1.641 g/cm³
LogP:3.40350
Water Solubility.:at 25 deg C (mg/L): 15.7
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:270.93026
Heavy Atom Count:14
Complexity:196

Purity/Quality:

99% ^*data from raw suppliers

3-((5-Bromothiazol-2-yl)oxy)phenol 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)OC2=NC=C(S2)Br)O

Technology Process of 3-(5-Bromothiazol-2-yloxy)phenol

There total 1 articles about 3-(5-Bromothiazol-2-yloxy)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 4175-78-4
2,5-dibromo-1,3-thiazole

: 108-46-3
recorcinol

: 904961-08-6
3-(5-bromo-thiazol-2-yloxy)-phenol

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 130 ℃; for 2h;

Reference yield: 75.0%

: 904961-08-6
3-(5-bromo-thiazol-2-yloxy)-phenol

: 42105-25-9
N-(1-methyl-prop-2-ynyl)acetamide

: 904961-03-1
N-{3-[2-(3-hydroxy-phenoxy)-thiazol-5-yl]-1-methyl-prop-2-ynyl}-acetamide

Guidance literature:: With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In tetrahydrofuran; at 75 ℃; for 2.5h;

Reference yield:

: 904961-08-6
3-(5-bromo-thiazol-2-yloxy)-phenol

: N-{3-[2-(3-methoxy-phenoxy)-thiazol-5-yl]-1-methyl-prop-2-ynyl}-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: Pd(PPh₃)2Cl₂; CuI; Et₃N / tetrahydrofuran / 80 °C

2: diethyl azodicarboxylate; PPh₃ / tetrahydrofuran / 20 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; 1: Sonogashira coupling / 2: Mitsunobu reaction;
DOI:10.1016/j.bmcl.2006.08.100