1-(4-bromophenyl)-2,2-dichloro-3-(4-methylphenyl)aziridine

Base Information

• Chemical Name: 1-(4-bromophenyl)-2,2-dichloro-3-(4-methylphenyl)aziridine
• CAS No.: 1336883-81-8
• Molecular Formula: C₁₅H₁₂BrCl₂N
• Molecular Weight: 357.077
• Mol file: 1336883-81-8.mol

Synonyms:1-(4-bromophenyl)-2,2-dichloro-3-(4-methylphenyl)aziridine

Chemical Property of 1-(4-bromophenyl)-2,2-dichloro-3-(4-methylphenyl)aziridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-bromophenyl)-2,2-dichloro-3-(4-methylphenyl)aziridine

There total 2 articles about 1-(4-bromophenyl)-2,2-dichloro-3-(4-methylphenyl)aziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

chloroform (67-66-3,8013-54-5) + N-(4-methylbenzyl)-4-bromoaniline (94612-47-2,124397-40-6,15486-64-3) → 1-(4-bromophenyl)-2,2-dichloro-3-(4-methylphenyl)aziridine (1336883-81-8)

Guidance literature:

With cetyltrimethylammonim bromide; sodium hydroxide; In water; for 0.183333h; Sonication;

DOI:10.1246/bcsj.20110106

Reference yield:

4-methyl-benzaldehyde (104-87-0) → 1-(4-bromophenyl)-2,2-dichloro-3-(4-methylphenyl)aziridine (1336883-81-8)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol / 20 °C

2: cetyltrimethylammonim bromide; sodium hydroxide / water / 20 °C

With cetyltrimethylammonim bromide; sodium hydroxide; In methanol; water;

DOI:10.1002/hlca.201100453

Reference yield: 96.0%

1-(4-bromophenyl)-2,2-dichloro-3-(4-methylphenyl)aziridine (1336883-81-8) → N-(4-bromophenyl)-N-[hydroxy(4-methylphenyl)methyl]formamide (1393934-70-7)

Guidance literature:

With water; dimethyl sulfoxide; at 70 ℃; for 3h;

DOI:10.1002/hlca.201100453

upstream raw materials:

chloroform

N-(4-methylbenzyl)-4-bromoaniline

4-methyl-benzaldehyde

Downstream raw materials:

N-(4-bromophenyl)-N-[hydroxy(4-methylphenyl)methyl]formamide