3-[2'-(S)-t-butoxycarbonylamino-3'-(4''-methoxycarbonylmethyl)benzene]propanoylamino-1-(4-methoxybenzyl)-4-methyl-2-pyridone

Base Information

Chemical Name:3-[2'-(S)-t-butoxycarbonylamino-3'-(4''-methoxycarbonylmethyl)benzene]propanoylamino-1-(4-methoxybenzyl)-4-methyl-2-pyridone
CAS No.:356578-34-2
Molecular Formula:C₃₁H₃₇N₃O₇
Molecular Weight:563.651
Hs Code.:

Synonyms:3-[2'-(S)-t-butoxycarbonylamino-3'-(4''-methoxycarbonylmethyl)benzene]propanoylamino-1-(4-methoxybenzyl)-4-methyl-2-pyridone

Suppliers and Price of 3-[2'-(S)-t-butoxycarbonylamino-3'-(4''-methoxycarbonylmethyl)benzene]propanoylamino-1-(4-methoxybenzyl)-4-methyl-2-pyridone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-[2'-(S)-t-butoxycarbonylamino-3'-(4''-methoxycarbonylmethyl)benzene]propanoylamino-1-(4-methoxybenzyl)-4-methyl-2-pyridone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-[2'-(S)-t-butoxycarbonylamino-3'-(4''-methoxycarbonylmethyl)benzene]propanoylamino-1-(4-methoxybenzyl)-4-methyl-2-pyridone

There total 4 articles about 3-[2'-(S)-t-butoxycarbonylamino-3'-(4''-methoxycarbonylmethyl)benzene]propanoylamino-1-(4-methoxybenzyl)-4-methyl-2-pyridone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

: 123993-31-7
(S)-α-<<(1,1-dimethylethoxy)carbonyl>amino>-4-<2-(methyloxy)-2-oxoethyl>benzenepropanoic acid

: 228410-49-9
3-amino-1-(4-methoxybenzyl)-4-methyl-2-pyridone

: 356578-34-2
3-[2'-(S)-t-butoxycarbonylamino-3'-(4''-methoxycarbonylmethyl)benzene]propanoylamino-1-(4-methoxybenzyl)-4-methyl-2-pyridone

Guidance literature:: (S)-α-<<(1,1-dimethylethoxy)carbonyl>amino>-4-<2-(methyloxy)-2-oxoethyl>benzenepropanoic acid; With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dichloromethane; at 0 ℃; for 0.333333h;

3-amino-1-(4-methoxybenzyl)-4-methyl-2-pyridone; In dichloromethane; at 0 - 20 ℃; Further stages.;
DOI:10.1021/jm000446q

Reference yield:

: 21901-18-8
4-Methyl-3-nitro-2-pyridone

: 356578-34-2
3-[2'-(S)-t-butoxycarbonylamino-3'-(4''-methoxycarbonylmethyl)benzene]propanoylamino-1-(4-methoxybenzyl)-4-methyl-2-pyridone

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaH / dimethylformamide / 1 h

1.2: 56 percent / dimethylformamide / 20 °C

2.1: 96 percent / H₂ / 10percent Pd/C / ethanol / 5.5 h / 2068.65 Torr

3.1: EDC / CH₂Cl₂ / 0.33 h / 0 °C

3.2: 27 percent / CH₂Cl₂ / 0 - 20 °C

With hydrogen; sodium hydride; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; 10percent Pd/C; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm000446q

Reference yield:

: 824-94-2
p-methoxybenzyl chloride

: 356578-34-2
3-[2'-(S)-t-butoxycarbonylamino-3'-(4''-methoxycarbonylmethyl)benzene]propanoylamino-1-(4-methoxybenzyl)-4-methyl-2-pyridone

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaH / dimethylformamide / 1 h

1.2: 56 percent / dimethylformamide / 20 °C

2.1: 96 percent / H₂ / 10percent Pd/C / ethanol / 5.5 h / 2068.65 Torr

3.1: EDC / CH₂Cl₂ / 0.33 h / 0 °C

3.2: 27 percent / CH₂Cl₂ / 0 - 20 °C

With hydrogen; sodium hydride; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; 10percent Pd/C; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm000446q