C₂₄H₁₆O₂Cl₂

Base Information

• Chemical Name: C₂₄H₁₆O₂Cl₂
• CAS No.: 942229-68-7
• Molecular Formula: C₂₄H₁₆Cl₂O₂
• Molecular Weight: 407.296
• Mol file: 942229-68-7.mol

Synonyms:C₂₄H₁₆O₂Cl₂

Chemical Property of C₂₄H₁₆O₂Cl₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₁₆O₂Cl₂

There total 2 articles about C₂₄H₁₆O₂Cl₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-n-chlorophenylacetylene (873-73-4) + o-phthalic dicarboxaldehyde (643-79-8) → C24H16O2Cl2 (942229-68-7)

Guidance literature:

4-n-chlorophenylacetylene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

o-phthalic dicarboxaldehyde; In tetrahydrofuran; hexane; at 20 ℃; for 2h; Inert atmosphere; Schlenk technique;

Reference yield:

1-Chloro-4-iodobenzene (637-87-6) + 1-[2-(1-hydroxy-prop-2-ynyl)-phenyl]-prop-2-yn-1-ol (141068-38-4) → C24H16O2Cl2 (942229-68-7)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; at 20 ℃;

DOI:10.1002/adsc.200800037

Reference yield: 83.0%

C24H16O2Cl2 (942229-68-7) + methyl chloroformate (79-22-1) → 1,1'-(1,2-phenylene)bis(3-(4-chlorophenyl)prop-2-yne-1,1-diyl)dimethyl dicarbonate

Guidance literature:

With pyridine; dmap; In dichloromethane; at 0 - 20 ℃; for 2h;

upstream raw materials:

4-n-chlorophenylacetylene

o-phthalic dicarboxaldehyde

1-Chloro-4-iodobenzene

1-[2-(1-hydroxy-prop-2-ynyl)-phenyl]-prop-2-yn-1-ol

Downstream raw materials:

acetic acid 1-{2-[1-acetoxy-3-(4-chloro-phenyl)-prop-2-ynyl]-phenyl}-3-(4-chloro-phenyl)-prop-2-ynyl ester

2-chloro-12-(4-chlorophenyl)-5-phenyltetracene

2-chloro-5,12-bis(4-chlorophenyl)tetracene

2-chloro-12-(4-chlorophenyl)-5-(4-(trifluoromethyl)phenyl)tetracene

Refernces

• 1、 Sun, Ning,Chen, Haoyi,Li, Xiangdong,Xu, Murong,Gan, Yi,Zhang, Liangwei,Liu, Yuanhong. "PBr3-mediated cyclization of 1,7-diyn-3,6-bis(propargyl carbonate)s: Synthesis of 5-bromotetracenes". . p. 10051 - 10061. Retrieved 2018/05/31.
• 2、 Chen, Ming,Liu, Jun,Wang, Lu,Zhou, Xiaobo,Liu, Yuanhong. "Gold-catalyzed cascade cycloisomerization of 1,7-diyn-3,6-bis(propargyl carbonate)s: Stereoselective synthesis of naphtho[b]cyclobutenes". supporting information. p. 8650 - 8652. Retrieved 2013/09/23.