N-(4'-tert-butoxycarbonylbenzyl)-N,N-dimethyl-N-{(1R)-1-[(-)-8-phenylmenthyloxycarbonylethyl]}ammonium bromide

Base Information

Chemical Name:N-(4'-tert-butoxycarbonylbenzyl)-N,N-dimethyl-N-{(1R)-1-[(-)-8-phenylmenthyloxycarbonylethyl]}ammonium bromide
CAS No.:1088481-85-9
Molecular Formula:Br*C₃₃H₄₈NO₄
Molecular Weight:602.652
Hs Code.:

Synonyms:N-(4'-tert-butoxycarbonylbenzyl)-N,N-dimethyl-N-{(1R)-1-[(-)-8-phenylmenthyloxycarbonylethyl]}ammonium bromide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4'-tert-butoxycarbonylbenzyl)-N,N-dimethyl-N-{(1R)-1-[(-)-8-phenylmenthyloxycarbonylethyl]}ammonium bromide

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Technology Process of N-(4'-tert-butoxycarbonylbenzyl)-N,N-dimethyl-N-{(1R)-1-[(-)-8-phenylmenthyloxycarbonylethyl]}ammonium bromide

There total 1 articles about N-(4'-tert-butoxycarbonylbenzyl)-N,N-dimethyl-N-{(1R)-1-[(-)-8-phenylmenthyloxycarbonylethyl]}ammonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1088482-39-6
C₂₁H₃₃NO₂

: 108052-76-2
4-(bromomethyl)benzoic acid 1,1-dimethylethyl ester

: 1088481-85-9
N-(4'-tert-butoxycarbonylbenzyl)-N,N-dimethyl-N-{(1R)-1-[(-)-8-phenylmenthyloxycarbonylethyl]}ammonium bromide

Guidance literature:: In acetonitrile; at 20 ℃; for 48h;
DOI:10.1039/b811162f

Reference yield: 92.0%

: 1088481-85-9
N-(4'-tert-butoxycarbonylbenzyl)-N,N-dimethyl-N-{(1R)-1-[(-)-8-phenylmenthyloxycarbonylethyl]}ammonium bromide

: 1088481-99-5
(2S)-2-(5'-tert-butoxycarbonyl-2'-methylphenyl)-2-dimethylaminopropionic acid (-)-8-phenylmenthol ester

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at -60 ℃; for 6h; diastereoselective reaction; Inert atmosphere;
DOI:10.1039/b811162f