2-Cyano-4'-methylbiphenyl

Base Information

• Chemical Name: 2-Cyano-4'-methylbiphenyl
• CAS No.: 93717-55-6
• Molecular Formula: C14H11N
• Molecular Weight: 193.248
• Hs Code.: 2926909090
• Mol file: 93717-55-6.mol

Synonyms:m-Tolunitrile,a-phenyl- (7CI);3-Benzylbenzonitrile;4'-Methylbiphenyl-2-carbonitrile;[1,1'-Biphenyl]-2-carbonitrile, 4'-methyl-;4'-Methyl[1,1'-biphenyl]-2-carbonitrile;Jsp001091;

Chemical Property of 2-Cyano-4'-methylbiphenyl

Chemical Property:

• Melting Point: 49-53 °C
• Boiling Point: 356.8 °C at 760 mmHg
• Flash Point: 170.4 °C
• PSA: 23.79000
• Density: 1.096 g/cm³
• LogP: 3.53368

Purity/Quality:

99% ^*data from raw suppliers

2-Cyano-4-methylbiphenyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 36/37/39-26-22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Cyano-4'-methylbiphenyl

There total 13 articles about 2-Cyano-4'-methylbiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

m-(bromomethyl)benzonitrile (28188-41-2) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 3-benzylbenzonitrile (93717-55-6)

Guidance literature:

With aluminium trichloride; for 10h; Heating;

Reference yield: 74.0%

3-cyanobromobenzene (6952-59-6) + benzyl chloride (100-44-7) → 3-benzylbenzonitrile (93717-55-6)

Guidance literature:

With 3-chloroprop-1-ene; trifluoroacetic acid; cobalt(II) bromide; zinc; In acetonitrile; at 20 ℃;

DOI:10.1039/b809626k

Reference yield: 72.0%

3-iodobenzonitrile (69113-59-3) + benzylic zinc mesylate → 3-benzylbenzonitrile (93717-55-6)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; for 3h; Inert atmosphere;

DOI:10.1055/s-0034-1379880

upstream raw materials:

3-(2-methoxy-1-phenylethyl)benzonitrile

m-(bromomethyl)benzonitrile

benzene

3-acethylbenzonitrile

Downstream raw materials:

ethyl 3-benzylbenzene-carboximidoate

[3-((phenylmethyl)phenyl)methyl]amine

3-benzoylbenzonitrile