[3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-acetic acid

Base Information

Chemical Name:[3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-acetic acid
CAS No.:959138-50-2
Molecular Formula:C₁₃H₁₂ClN₃O₃
Molecular Weight:293.71
Hs Code.:

Synonyms:[3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-acetic acid

Suppliers and Price of [3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-acetic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-acetic acid

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of [3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-acetic acid

There total 2 articles about [3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 959138-11-5
ethyl [3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-acetate

: 959138-50-2
[3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-acetic acid

Guidance literature:: ethyl [3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-acetate; With water; potassium hydroxide; In methanol; at 20 ℃; for 2h;

With hydrogenchloride; water; In methanol; pH=~ 1;

Reference yield: 79.0%

: 959137-76-9
5-(4-chloro-phenyl)-4-(2-methoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

: 105-39-5
chloroacetic acid ethyl ester

: 959138-50-2
[3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-acetic acid

Guidance literature:: 5-(4-chloro-phenyl)-4-(2-methoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one; chloroacetic acid ethyl ester; With potassium carbonate; In acetonitrile; for 3h; Reflux;

With water; potassium hydroxide; In methanol; at 20 ℃; for 4h;

With hydrogenchloride; water; In methanol; pH=3;

Reference yield: 99.0%

: 2740-83-2
3-(TRIFLUOROMETHYL)BENZYLAMINE

: 959138-50-2
[3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-acetic acid

: 959130-68-8
2-[3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-N-[3-(trifluoro-methyl)phenylmethyl]-acetamide

Guidance literature:: 3-(TRIFLUOROMETHYL)BENZYLAMINE; [3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-acetic acid; With benzotriazol-1-ol; In N,N-dimethyl-formamide; for 0.166667h;

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃;