sodium (2R)-<2-²H₁>propanoate

Base Information

• Chemical Name: sodium (2R)-<2-²H₁>propanoate
• CAS No.: 73493-56-8
• Molecular Formula: C₃H₅O₂*Na
• Molecular Weight: 97.0533
• Mol file: 73493-56-8.mol

Synonyms:sodium (2R)-<2-²H₁>propanoate

Chemical Property of sodium (2R)-<2-²H₁>propanoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of sodium (2R)-<2-²H₁>propanoate

There total 3 articles about sodium (2R)-<2-²H₁>propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1,1,2-2H3)-1-propanol → sodium proprionate (137-40-6) + sodium (2R)-<2-2H1>propanoate (73493-56-8) + sodium (2S)-<2-2H1>propanoate (123701-28-0)

Guidance literature:

With oxygen; sodium hydrogencarbonate; platinum; In water; at 23 ℃; for 144h;

Reference yield:

ethyl (S)-2-[[(4-methylphenyl)sulfonyl]oxy]propanoate (57057-80-4) → sodium (2R)-<2-2H1>propanoate (73493-56-8)

Guidance literature:

With sodium hydroxide; sodium borodeuteride; Yield given. Multistep reaction; 1.) 100 deg C, 48 h, 2.) ethanol, RT, 2 h;

DOI:10.1021/jo00287a031

Reference yield:

(S)-2-bromopropanoic acid (32644-15-8,10327-08-9) → sodium (2R)-<2-2H1>propanoate (73493-56-8)

Guidance literature:

With lithium triethyl borodeuteride; In tetrahydrofuran; at 2 ℃; Heating;

upstream raw materials:

(S)-2-bromopropanoic acid

ethyl (S)-2-[[(4-methylphenyl)sulfonyl]oxy]propanoate

Downstream raw materials:

(2R,2'S)-2-(1-oxopropoxy-2-d)-2-phenylacetic acid methyl ester

Refernces

• 1、 Sood, Gulshan R.,Ashworth, Doreen M.,Ajaz, Abid A.,Robinson, John A.. "BIOSYNTHESIS OF THE POLYETHER ANTIBIOTIC MONENSIN-A. RESULTS FROM THE INCORPORATIONS OF LABELLED ACETATE AND PROPIONATE AS A PROBE OF THE CARBON CHAIN ASSEMBLY PROCESSES". . p. 3183 - 3194. Retrieved 2007/10/02.