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d9-docetaxel-2'-O-alaninate

Base Information
  • Chemical Name:d9-docetaxel-2'-O-alaninate
  • CAS No.:1383561-40-7
  • Molecular Formula:C46H58N2O15
  • Molecular Weight:887.899
  • Hs Code.:
d<sub>9</sub>-docetaxel-2'-O-alaninate

Synonyms:d9-docetaxel-2'-O-alaninate

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The product has achieved commercial mass production*data from LookChem market partment
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Chemical Property of d9-docetaxel-2'-O-alaninate
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Technology Process of d9-docetaxel-2'-O-alaninate

There total 5 articles about d9-docetaxel-2'-O-alaninate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; for 3h; under 1551.49 Torr;
Guidance literature:
Multi-step reaction with 4 steps
1.1: formic acid / 4 h / 20 °C
2.1: triethylamine / acetonitrile / 5 h / 20 °C
3.1: dmap; toluene-4-sulfonic acid; diisopropyl-carbodiimide / dichloromethane / 0.08 h / Cooling with ice
3.2: 4.5 h / 20 °C / Acidic conditions
4.1: hydrogen; palladium 10% on activated carbon / tetrahydrofuran / 3 h / 1551.49 Torr
With dmap; formic acid; palladium 10% on activated carbon; hydrogen; toluene-4-sulfonic acid; triethylamine; diisopropyl-carbodiimide; In tetrahydrofuran; dichloromethane; acetonitrile;
Guidance literature:
Multi-step reaction with 2 steps
1.1: dmap; toluene-4-sulfonic acid; diisopropyl-carbodiimide / dichloromethane / 0.08 h / Cooling with ice
1.2: 4.5 h / 20 °C / Acidic conditions
2.1: hydrogen; palladium 10% on activated carbon / tetrahydrofuran / 3 h / 1551.49 Torr
With dmap; palladium 10% on activated carbon; hydrogen; toluene-4-sulfonic acid; diisopropyl-carbodiimide; In tetrahydrofuran; dichloromethane;
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