5-chloro-1-[5-chloro-2-(methylsulfonyl)benzyl]-2-imino-1,2-dihydropyridine-3-carboxamide monohydrochloride

Base Information

Chemical Name:5-chloro-1-[5-chloro-2-(methylsulfonyl)benzyl]-2-imino-1,2-dihydropyridine-3-carboxamide monohydrochloride
CAS No.:1192347-42-4
Molecular Formula:C₁₄H₁₃Cl₂N₃O₃S*ClH
Molecular Weight:410.708
Hs Code.:

Synonyms:5-chloro-1-[5-chloro-2-(methylsulfonyl)benzyl]-2-imino-1,2-dihydropyridine-3-carboxamide monohydrochloride

Suppliers and Price of 5-chloro-1-[5-chloro-2-(methylsulfonyl)benzyl]-2-imino-1,2-dihydropyridine-3-carboxamide monohydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-chloro-1-[5-chloro-2-(methylsulfonyl)benzyl]-2-imino-1,2-dihydropyridine-3-carboxamide monohydrochloride

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 5-chloro-1-[5-chloro-2-(methylsulfonyl)benzyl]-2-imino-1,2-dihydropyridine-3-carboxamide monohydrochloride

There total 2 articles about 5-chloro-1-[5-chloro-2-(methylsulfonyl)benzyl]-2-imino-1,2-dihydropyridine-3-carboxamide monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 70097-69-7
2-cyano-2-(3,4-dichloro-5-oxo-2,5-dihydrofuran-2-yl)acetamide

: 1-[5-chloro-2-(methylsulfonyl)phenyl]methanamine monohydrochloride

: 1192347-42-4
5-chloro-1-[5-chloro-2-(methylsulfonyl)benzyl]-2-imino-1,2-dihydropyridine-3-carboxamide monohydrochloride

Guidance literature:: 2-cyano-2-(3,4-dichloro-5-oxo-2,5-dihydrofuran-2-yl)acetamide; 1-[5-chloro-2-(methylsulfonyl)phenyl]methanamine monohydrochloride; With potassium carbonate; In ethanol; at 85 ℃;

With hydrogenchloride; In methanol; ethyl acetate; at 20 ℃;
DOI:10.1021/acs.jmedchem.5b01528

Reference yield:

: 58483-97-9
2-amino-5-chloropyridine-3-carboxamide

: 1192347-45-7
2-(bromomethyl)-4-chloro-1-(methylsulfonyl)benzene

: 1192347-42-4
5-chloro-1-[5-chloro-2-(methylsulfonyl)benzyl]-2-imino-1,2-dihydropyridine-3-carboxamide monohydrochloride

Guidance literature:: 2-amino-5-chloropyridine-3-carboxamide; 2-(bromomethyl)-4-chloro-1-(methylsulfonyl)benzene; In N,N-dimethyl-formamide; at 100 ℃; for 3h;

With sodium hydrogencarbonate; In water;

With hydrogenchloride; In methanol; ethyl acetate;