Acetoxy-[2-oxo-4-(4-phenyl-but-3-ynyl)-azetidin-1-yl]-acetic acid isopropyl ester

Base Information

Chemical Name:Acetoxy-[2-oxo-4-(4-phenyl-but-3-ynyl)-azetidin-1-yl]-acetic acid isopropyl ester
CAS No.:200421-09-6
Molecular Formula:C₂₀H₂₃NO₅
Molecular Weight:357.406
Hs Code.:

Synonyms:Acetoxy-[2-oxo-4-(4-phenyl-but-3-ynyl)-azetidin-1-yl]-acetic acid isopropyl ester

Suppliers and Price of Acetoxy-[2-oxo-4-(4-phenyl-but-3-ynyl)-azetidin-1-yl]-acetic acid isopropyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Acetoxy-[2-oxo-4-(4-phenyl-but-3-ynyl)-azetidin-1-yl]-acetic acid isopropyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Acetoxy-[2-oxo-4-(4-phenyl-but-3-ynyl)-azetidin-1-yl]-acetic acid isopropyl ester

There total 3 articles about Acetoxy-[2-oxo-4-(4-phenyl-but-3-ynyl)-azetidin-1-yl]-acetic acid isopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 108-24-7
acetic anhydride

: 200421-03-0
Hydroxy-[2-oxo-4-(4-phenyl-but-3-ynyl)-azetidin-1-yl]-acetic acid isopropyl ester

: 200421-09-6
Acetoxy-[2-oxo-4-(4-phenyl-but-3-ynyl)-azetidin-1-yl]-acetic acid isopropyl ester

Guidance literature:: With pyridine; In dichloromethane;
DOI:10.1021/jo971433w

Reference yield:

: 124991-87-3
(4-iodobut-1-yn-1-yl)benzene

: 200421-09-6
Acetoxy-[2-oxo-4-(4-phenyl-but-3-ynyl)-azetidin-1-yl]-acetic acid isopropyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) t-BuLi, 2.) lithium 2-thienylcyanocuprate / 1.) THF, -78 deg C, 2.) THF, 0 deg C, 3.) THF, 0 deg C

2: 77 percent / toluene; dimethylformamide / Heating

3: 82 percent / pyridine / CH₂Cl₂

With pyridine; tert.-butyl lithium; thien-2-yl(cyano)copper lithium; In dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo971433w

Reference yield:

: 200420-97-9
4-(4-Phenyl-but-3-ynyl)-azetidin-2-one

: 200421-09-6
Acetoxy-[2-oxo-4-(4-phenyl-but-3-ynyl)-azetidin-1-yl]-acetic acid isopropyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / toluene; dimethylformamide / Heating

2: 82 percent / pyridine / CH₂Cl₂

With pyridine; In dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo971433w