(S)-N-(1-benzyl-2-methoxyethyl)-2-(trifluoromethanesulfonyloxy)naphthalenecarboxamide

Base Information

Chemical Name:(S)-N-(1-benzyl-2-methoxyethyl)-2-(trifluoromethanesulfonyloxy)naphthalenecarboxamide
CAS No.:344799-64-0
Molecular Formula:C₂₂H₂₀F₃NO₅S
Molecular Weight:467.466
Hs Code.:

Synonyms:(S)-N-(1-benzyl-2-methoxyethyl)-2-(trifluoromethanesulfonyloxy)naphthalenecarboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-N-(1-benzyl-2-methoxyethyl)-2-(trifluoromethanesulfonyloxy)naphthalenecarboxamide

Chemical Property:

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Technology Process of (S)-N-(1-benzyl-2-methoxyethyl)-2-(trifluoromethanesulfonyloxy)naphthalenecarboxamide

There total 3 articles about (S)-N-(1-benzyl-2-methoxyethyl)-2-(trifluoromethanesulfonyloxy)naphthalenecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 358-23-6
trifluoromethylsulfonic anhydride

: 344799-63-9
(S)-N-(1-benzyl-2-methoxyethyl)-2-hydroxynaphthalenecarboxamide

: 344799-64-0
(S)-N-(1-benzyl-2-methoxyethyl)-2-(trifluoromethanesulfonyloxy)naphthalenecarboxamide

Guidance literature:: With pyridine; In benzene; at 20 ℃; for 6h;
DOI:10.1016/S0957-4166(01)00037-4

Reference yield:

: 947-65-9
methyl 2-hydroxy-1-naphthoate

: 344799-64-0
(S)-N-(1-benzyl-2-methoxyethyl)-2-(trifluoromethanesulfonyloxy)naphthalenecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / trimethylaluminium / benzene; hexane

2: 95 percent / pyridine / benzene / 6 h / 20 °C

With pyridine; trimethylaluminum; In hexane; benzene;
DOI:10.1016/S0957-4166(01)00037-4

Reference yield:

: 64715-81-7
(S)-(-)-2-amino-1-methoxy-3-phenylpropane hydrochloride

: 344799-64-0
(S)-N-(1-benzyl-2-methoxyethyl)-2-(trifluoromethanesulfonyloxy)naphthalenecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / trimethylaluminium / benzene; hexane

2: 95 percent / pyridine / benzene / 6 h / 20 °C

With pyridine; trimethylaluminum; In hexane; benzene;
DOI:10.1016/S0957-4166(01)00037-4