Technology Process of C20H24N2O3
There total 5 articles about C20H24N2O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(1S,2S)-2-phenylcyclopropane-1-carboxylic acid;
With
O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine;
In
N,N-dimethyl-formamide;
for 0.0916667h;
(R)-2-amino-2-(6-propoxypyridin-3-yl)-ethanol;
In
N,N-dimethyl-formamide;
for 1h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrogenchloride / methanol; diethyl ether / 0 - 20 °C / Inert atmosphere
2.1: triethylamine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / N,N-dimethyl-formamide / 0.09 h
2.2: 1 h
With
hydrogenchloride; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine;
In
methanol; diethyl ether; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: tert.-butyl lithium / tetrahydrofuran; pentane / 0.5 h / -78 °C
1.2: -78 - 20 °C / Inert atmosphere
2.1: hydrogenchloride / methanol; diethyl ether / 0 - 20 °C / Inert atmosphere
3.1: triethylamine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / N,N-dimethyl-formamide / 0.09 h
3.2: 1 h
With
hydrogenchloride; tert.-butyl lithium; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine;
In
tetrahydrofuran; methanol; diethyl ether; N,N-dimethyl-formamide; pentane;
