N-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)-N-ethyl-4-methoxylbenzamide

Base Information

Chemical Name:N-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)-N-ethyl-4-methoxylbenzamide
CAS No.:1570522-62-1
Molecular Formula:C₂₃H₂₉ClN₂O₂
Molecular Weight:400.948
Hs Code.:

Synonyms:N-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)-N-ethyl-4-methoxylbenzamide

Suppliers and Price of N-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)-N-ethyl-4-methoxylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)-N-ethyl-4-methoxylbenzamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)-N-ethyl-4-methoxylbenzamide

There total 4 articles about N-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)-N-ethyl-4-methoxylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1272306-01-0
N-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)ethanamine

: 100-07-2
4-methoxy-benzoyl chloride

: 1570522-62-1
N-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)-N-ethyl-4-methoxylbenzamide

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 ℃; for 24h;
DOI:10.1016/j.bmcl.2014.01.032

Reference yield:

: 1-(1-(4-chlorobenzyl)piperidin-4-yl)-N-ethylidenemethanamine

: 1570522-62-1
N-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)-N-ethyl-4-methoxylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol / 20 °C

2: triethylamine / tetrahydrofuran / 24 h / 0 °C

With sodium tetrahydroborate; triethylamine; In tetrahydrofuran; methanol;
DOI:10.1016/j.bmcl.2014.01.032

Reference yield:

: 1567842-52-7
(E)-N-ethylidene-1-(piperidin-4-yl)methanamine

: 1570522-62-1
N-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)-N-ethyl-4-methoxylbenzamide

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / acetone / 12 h / Reflux

2: sodium tetrahydroborate / methanol / 20 °C

3: triethylamine / tetrahydrofuran / 24 h / 0 °C

With sodium tetrahydroborate; potassium carbonate; triethylamine; In tetrahydrofuran; methanol; acetone;
DOI:10.1016/j.bmcl.2014.01.032