2-[(2-fluoro-6-trifluoromethylbenzoyl)-amino]-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid propylamide

Base Information

Chemical Name:2-[(2-fluoro-6-trifluoromethylbenzoyl)-amino]-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid propylamide
CAS No.:1370345-50-8
Molecular Formula:C₁₉H₁₈F₄N₂O₃S
Molecular Weight:430.423
Hs Code.:

Synonyms:2-[(2-fluoro-6-trifluoromethylbenzoyl)-amino]-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid propylamide

Suppliers and Price of 2-[(2-fluoro-6-trifluoromethylbenzoyl)-amino]-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid propylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[(2-fluoro-6-trifluoromethylbenzoyl)-amino]-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid propylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[(2-fluoro-6-trifluoromethylbenzoyl)-amino]-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid propylamide

There total 4 articles about 2-[(2-fluoro-6-trifluoromethylbenzoyl)-amino]-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid propylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 107-10-8,42939-71-9
propylamine

: 1370345-54-2
C₁₆H₁₁F₄NO₄S

: 1370345-50-8
2-[(2-fluoro-6-trifluoromethylbenzoyl)-amino]-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid propylamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;
DOI:10.1016/j.bmcl.2012.01.121

Reference yield:

: C₁₈H₁₅F₄NO₄S

: 1370345-50-8
2-[(2-fluoro-6-trifluoromethylbenzoyl)-amino]-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid propylamide

Guidance literature:: Multi-step reaction with 2 steps

1: water; potassium hydroxide / ethanol / 1 h / Reflux

2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 24 h / 20 °C

With water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium hydroxide; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.01.121

Reference yield:

: 117642-16-7
2-amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid ethyl ester

: 1370345-50-8
2-[(2-fluoro-6-trifluoromethylbenzoyl)-amino]-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid propylamide

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / tetrahydrofuran / 20 °C / Inert atmosphere

2: water; potassium hydroxide / ethanol / 1 h / Reflux

3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 24 h / 20 °C

With water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium hydroxide; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.01.121