3-Bromo-4-(4-methoxyphenyl)pyridine

Base Information

Chemical Name:3-Bromo-4-(4-methoxyphenyl)pyridine
CAS No.:88345-97-5
Molecular Formula:C12H10BrNO
Molecular Weight:264.12
Hs Code.:2933399090
DSSTox Substance ID:DTXSID40463473
Nikkaji Number:J1.608.502B
Wikidata:Q82288363
Mol file:88345-97-5.mol

Synonyms:3-bromo-4-(4-methoxyphenyl)pyridine;3-Bromo-4-(4'-methoxyphenyl)pyridine;88345-97-5;DTXSID40463473

Suppliers and Price of 3-Bromo-4-(4-methoxyphenyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-BROMO-4-(4'-METHOXYPHENYL)PYRIDINE 95.00%
5G
$ 1056.36

Total 9 raw suppliers

Chemical Property of 3-Bromo-4-(4-methoxyphenyl)pyridine

Chemical Property:

Vapor Pressure:0.000294mmHg at 25°C
Refractive Index:1.587
Boiling Point:331.8 °C at 760 mmHg
Flash Point:154.5 °C
PSA：22.12000
Density:1.403 g/cm³
LogP:3.51970
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:262.99458
Heavy Atom Count:15
Complexity:192

Purity/Quality:

98% ^*data from raw suppliers

3-BROMO-4-(4'-METHOXYPHENYL)PYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=C(C=NC=C2)Br

Technology Process of 3-Bromo-4-(4-methoxyphenyl)pyridine

There total 4 articles about 3-Bromo-4-(4-methoxyphenyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 626-55-1,163928-56-1
3-Bromopyridine

: 696-62-8
para-iodoanisole

: 88345-97-5
3-bromo-4-(4'-methoxyphenyl)pyridine

Guidance literature:: 3-Bromopyridine; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -95 ℃;

With zinc(II) chloride; In tetrahydrofuran; hexane; at -95 - 20 ℃;

para-iodoanisole; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; Further stages.; Heating;
DOI:10.1021/ol006986z

Reference yield:

: 626-55-1,163928-56-1
3-Bromopyridine

: 88345-97-5
3-bromo-4-(4'-methoxyphenyl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 0.25 h / -20 °C

2: 2) o-chloranil / 1) THF, -20 deg C, 15 min, 2) toluene, reflux, 6 h

With o-tetrachloroquinone; In tetrahydrofuran;

Reference yield:

: 90731-83-2
3-bromo-1-(phenoxycarbonyl)pyridinium chloride

: 13139-86-1
4-methoxyphenyl magnesium bromide

: 88345-97-5
3-bromo-4-(4'-methoxyphenyl)pyridine

Guidance literature:: With copper(l) iodide; dimethylsulfide; chloranil; Multistep reaction; 1) THF, -20 deg C, 15 min, 2) toluene, reflux, 6 h;