(S)-4-(1-methylpropyl)oxyaniline

Base Information

• Chemical Name: (S)-4-(1-methylpropyl)oxyaniline
• CAS No.: 1052612-68-6
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.235
• Mol file: 1052612-68-6.mol

Synonyms:(S)-4-(1-methylpropyl)oxyaniline

Chemical Property of (S)-4-(1-methylpropyl)oxyaniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-4-(1-methylpropyl)oxyaniline

There total 4 articles about (S)-4-(1-methylpropyl)oxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) → (S)-4-(1-methylpropyl)oxyaniline (1052612-68-6)

Guidance literature:

Multi-step reaction with 2 steps

1: di-isopropyl azodicarboxylate / tetrahydrofuran

2: tin(II) chloride dihdyrate

With tin(II) chloride dihdyrate; di-isopropyl azodicarboxylate; In tetrahydrofuran;

DOI:10.1002/anie.202109084

Reference yield:

(S)-4-(1-methylpropyl)oxy-1-nitrobenzene (1054554-15-2) → (S)-4-(1-methylpropyl)oxyaniline (1052612-68-6)

Guidance literature:

With nickel; hydrazine; In ethanol; water;

DOI:10.1039/b901384a

Reference yield:

4-acetaminophenol (103-90-2,8055-08-1) → (S)-4-(1-methylpropyl)oxyaniline (1052612-68-6)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / acetone / 32 h

2: aq. HCl

With hydrogenchloride; potassium carbonate; In acetone;

DOI:10.1080/10587250108025027

upstream raw materials:

4-acetaminophenol

(S)-4-(1-methylpropyl)oxy-1-nitrobenzene

4-nitro-phenol

Refernces

• 1、 Cheng, Xiaoxiao,Ma, Yafei,Miao, Tengfei,Zhang, Wei,Zhu, Xiaoyan,Zhu, Xiulin. "Controlling the Multiple Chiroptical Inversion in Biphasic Liquid-Crystalline Polymers". supporting information. p. 24430 - 24436. Retrieved 2021/10/12.