cyclohex-2-enyl carbamate

Base Information

• Chemical Name: cyclohex-2-enyl carbamate
• CAS No.: 119449-77-3
• Molecular Formula: C₇H₁₁NO₂
• Molecular Weight: 141.17
• Mol file: 119449-77-3.mol

Synonyms:cyclohex-2-enyl carbamate

Chemical Property of cyclohex-2-enyl carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyclohex-2-enyl carbamate

There total 6 articles about cyclohex-2-enyl carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

Cyclohex-2-enol (822-67-3) + methyl carbamate (598-55-0) → cyclohex-2-enyl carbamate (119449-77-3)

Guidance literature:

With di-n-butyltin maleate; In toluene; for 3h; Reflux;

DOI:10.1055/s-0040-1708020

Reference yield: 92.0%

carbamic acid phenyl ester (622-46-8) + Cyclohex-2-enol (822-67-3) → cyclohex-2-enyl carbamate (119449-77-3)

Guidance literature:

With di-n-butyltin maleate; In toluene; at 90 ℃; for 4h;

DOI:10.1055/s-0030-1258102

Reference yield: 74.0%

2,2,2-trifluoroacetyl isocyanate (14565-32-3) + Cyclohex-2-enol (822-67-3) → cyclohex-2-enyl carbamate (119449-77-3)

Guidance literature:

2,2,2-trifluoroacetyl isocyanate; Cyclohex-2-enol; In dichloromethane; at 0 ℃; for 2h;

With potassium carbonate; In methanol; for 4h; Further stages.;

DOI:10.1021/ja0276117

upstream raw materials:

(2,2,2-trichloroacetyl)carbamic acid cyclohex-2-enyl ester

Cyclohex-2-enol

Trichloroacetyl isocyanate

2,2,2-trifluoroacetyl isocyanate

Downstream raw materials:

N-(cyclohex-2-enyl) methyl carbamate

4-hydroxyhexahydrobenzooxazol-2-one

3-Isocyanato-cyclohexene

N-(1-cyclohex-2-enyl)acetamide

Refernces

• 1、 Hasegawa, Tomoyuki,Ichikawa, Yoshiyasu,Masuda, Toshiya,Minami, Takahiro,Morishita, Yukinori,Ochi, Rika,Sato, Hiroshi. "Further development of the tin-catalyzed transcarbamoylation reaction". supporting information. p. 2373 - 2378. Retrieved 2020/08/19.
• 2、 Ichikawa, Yoshiyasu,Osada, Masafumi,Ohtani, Ikuko I.,Isobe, Minoru. "A new synthetic method for the preparation of amino sugars through an allyl cyanate-to-isocyanate rearrangement". . p. 1449 - 1455. Retrieved 2007/10/03.