4-(3-Chlorophenylsulfonylaminomethyl)benzoic acid

Base Information

Chemical Name:4-(3-Chlorophenylsulfonylaminomethyl)benzoic acid
CAS No.:690645-98-8
Molecular Formula:C₁₄H₁₂ClNO₄S
Molecular Weight:325.773
Hs Code.:
DSSTox Substance ID:DTXSID101204462
Mol file:690645-98-8.mol

Synonyms:690645-98-8;4-(3-Chlorophenylsulfonylaminomethyl)benzoic acid;4-(((3-chlorophenyl)sulfonamido)methyl)benzoic acid;4-[[(3-chlorophenyl)sulfonylamino]methyl]benzoic acid;4-(([(3-CHLOROPHENYL)SULFONYL]AMINO)METHYL)BENZOIC ACID;4-[[[(3-Chlorophenyl)sulfonyl]amino]methyl]benzoic acid;AQ-750/42501915;DTXSID101204462;MFCD04154033;AKOS000813209;VU0618384-1;EN300-236157;4-[(3-chlorobenzenesulfonamido)methyl]benzoic acid;Z45512198;F3394-1126

Suppliers and Price of 4-(3-Chlorophenylsulfonylaminomethyl)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alfa Aesar
4-(3-Chlorophenylsulfonylaminomethyl)benzoic acid, 96%
1g
$ 72.40

Alfa Aesar
4-(3-Chlorophenylsulfonylaminomethyl)benzoic acid, 96%
250mg
$ 26.90

Total 6 raw suppliers

Chemical Property of 4-(3-Chlorophenylsulfonylaminomethyl)benzoic acid

Chemical Property:

Melting Point:217-219℃
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:325.0175567
Heavy Atom Count:21
Complexity:454

Purity/Quality:

99% ^*data from raw suppliers

4-(3-Chlorophenylsulfonylaminomethyl)benzoic acid, 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)Cl)S(=O)(=O)NCC2=CC=C(C=C2)C(=O)O
Uses 4-[[[(3-Chlorophenyl)sulfonyl]amino]methyl]benzoic Acid is a selective inhibitor of the 11β-hydroxysteroid dehydrogenase type 1

Technology Process of 4-(3-Chlorophenylsulfonylaminomethyl)benzoic acid

There total 1 articles about 4-(3-Chlorophenylsulfonylaminomethyl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1186212-01-0
methyl 4-[(3-chlorophenylsulfonamido)methyl]benzoate

: 690645-98-8
4-[(3-chlorophenylsulfonamido)methyl]benzoic acid

Guidance literature:: With potassium hydroxide; In methanol; at 60 ℃; for 4h;
DOI:10.1016/j.bmcl.2009.05.033

Reference yield: 79.0%

: 123-75-1
pyrrolidine

: 690645-98-8
4-[(3-chlorophenylsulfonamido)methyl]benzoic acid

: 727689-14-7
3-chloro-N-[4-(pyrrolidine-1-carbonyl)benzyl]benzenesulfonamide

Guidance literature:: 4-[(3-chlorophenylsulfonamido)methyl]benzoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 1h;

pyrrolidine; In dichloromethane; for 12h;
DOI:10.1016/j.bmcl.2009.05.033

Reference yield: 76.0%

: 690645-98-8
4-[(3-chlorophenylsulfonamido)methyl]benzoic acid

: 108-91-8,157973-60-9
cyclohexylamine

: 1186211-94-8
4-[(3-chlorophenylsulfonamido)methyl]-N-cyclohexylbenzamide

Guidance literature:: 4-[(3-chlorophenylsulfonamido)methyl]benzoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 1h;

cyclohexylamine; In dichloromethane; for 12h;
DOI:10.1016/j.bmcl.2009.05.033