Technology Process of C24H23F3N2O5
There total 3 articles about C24H23F3N2O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tributylphosphine; 1,1'-azodicarbonyl-dipiperidine;
In
tetrahydrofuran;
at 20 - 80 ℃;
chemoselective reaction;
Inert atmosphere;
DOI:10.1021/ml300209g
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 2-chloropropionyl chloride / methanol / 20 °C / Inert atmosphere
2: 1,1'-azodicarbonyl-dipiperidine; tributylphosphine / tetrahydrofuran / 20 - 80 °C / Inert atmosphere
With
2-chloropropionyl chloride; tributylphosphine; 1,1'-azodicarbonyl-dipiperidine;
In
tetrahydrofuran; methanol;
2: |Mitsunobu Displacement;
DOI:10.1021/ml300209g
- Guidance literature:
-
Multi-step reaction with 3 steps
1: triethylamine / dichloromethane / 0 °C / Inert atmosphere
2: 2-chloropropionyl chloride / methanol / 20 °C / Inert atmosphere
3: 1,1'-azodicarbonyl-dipiperidine; tributylphosphine / tetrahydrofuran / 20 - 80 °C / Inert atmosphere
With
2-chloropropionyl chloride; tributylphosphine; triethylamine; 1,1'-azodicarbonyl-dipiperidine;
In
tetrahydrofuran; methanol; dichloromethane;
3: |Mitsunobu Displacement;
DOI:10.1021/ml300209g