2,5-Dioxopyrrolidin-1-yl 3-(2-bromoacetamido)propanoate

Base Information

Chemical Name:2,5-Dioxopyrrolidin-1-yl 3-(2-bromoacetamido)propanoate
CAS No.:57159-62-3
Molecular Formula:C₉H₁₁BrN₂O₅
Molecular Weight:307.101
Hs Code.:2925190090
European Community (EC) Number:862-990-8
DSSTox Substance ID:DTXSID30403560
Nikkaji Number:J508.349D
Wikidata:Q82207258
Mol file:57159-62-3.mol

Synonyms:57159-62-3;N-Succinimidyl 3-(Bromoacetamido)propionate;2,5-dioxopyrrolidin-1-yl 3-(2-bromoacetamido)propanoate;3-(2-bromoacetamido)propanoic acid NHS ester;Succinimidyl 3-(bromoacetamido)propionate;(2,5-dioxopyrrolidin-1-yl) 3-[(2-bromoacetyl)amino]propanoate;WGMMKWFUXPMTRW-UHFFFAOYSA-N;SCHEMBL43231;DTXSID30403560;AMY27295;MFCD01863457;ZB0752;AKOS016014393;BP-21084;BS-42583;HY-141385;A8154;CS-0114534;FT-0604061;C70372;3-(2-BROMOACETAMIDO)PROPANOICACIDNHSESTER;SBAP (succinimidyl 3-(bromoacetamido)propionate);2,5-Dioxopyrrolidin-1-yl N-(bromoacetyl)-beta-alaninate

Suppliers and Price of 2,5-Dioxopyrrolidin-1-yl 3-(2-bromoacetamido)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Succinimidyl3-(Bromoacetamido)propionate
100mg
$ 1060.00

SynQuest Laboratories
2,5-Dioxopyrrolidin-1-yl 3-(2-bromoacetamido)propanoate
100 mg
$ 416.00

Medical Isotopes, Inc.
N-Succinimidyl3-(Bromoacetamido)propionate
10 mg
$ 820.00

Iris Biotech GmbH
SBAPLinker
5 g
$ 1620.00

Iris Biotech GmbH
SBAPLinker
1 g
$ 405.00

Crysdot
2,5-Dioxopyrrolidin-1-yl3-(2-bromoacetamido)propanoate 97%
1g
$ 589.00

Chemenu
2,5-dioxopyrrolidin-1-yl3-(2-bromoacetamido)propanoate 97%
1g
$ 556.00

BroadPharm
3-(2-bromoacetamido)propanoicacidNHSester 92%
250 MG
$ 350.00

American Custom Chemicals Corporation
N-SUCCINIMIDYL 3-(BROMOACETAMIDO)PROPIONATE 95.00%
10MG
$ 739.20

Alichem
2,5-Dioxopyrrolidin-1-yl3-(2-bromoacetamido)propanoate
1g
$ 518.40

Total 26 raw suppliers

Chemical Property of 2,5-Dioxopyrrolidin-1-yl 3-(2-bromoacetamido)propanoate

Chemical Property:

Appearance/Colour:White Solid
Melting Point:93-94 °C
Refractive Index:1.566
PKA:12.96±0.46(Predicted)
PSA：92.78000
Density:1.69 g/cm³
LogP:-0.17640
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
Solubility.:Chloroform (Slightly, Heated), Methanol (Slightly)
XLogP3:-0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:305.98513
Heavy Atom Count:17
Complexity:341

Purity/Quality:

97% ^*data from raw suppliers

N-Succinimidyl3-(Bromoacetamido)propionate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)N(C1=O)OC(=O)CCNC(=O)CBr
Description 3-(2-bromoacetamido)propanoic acid NHS ester is a PEG linker containing a bromide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Uses A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 6.2 Angstroms A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 6.2 Angstroms

Technology Process of 2,5-Dioxopyrrolidin-1-yl 3-(2-bromoacetamido)propanoate

There total 2 articles about 2,5-Dioxopyrrolidin-1-yl 3-(2-bromoacetamido)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.6%