Imidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one

Base Information

Chemical Name:Imidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one
CAS No.:240815-49-0
Molecular Formula:C₉H₆N₄O
Molecular Weight:186.173
Hs Code.:
DSSTox Substance ID:DTXSID40579028
Nikkaji Number:J1.528.948A
Wikidata:Q82469420
Mol file:240815-49-0.mol

Synonyms:240815-49-0;Imidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one;IMIDAZO[1,5-A]PYRIDO[3,2-E]PYRAZIN-6-OL;2,4,8,13-tetrazatricyclo[7.4.0.02,6]trideca-1(9),3,5,10,12-pentaen-7-one;SCHEMBL249873;DTXSID40579028;AKOS006352462;AB44512;C90437;2-Amino-4-methoxycarbonyl)benzeneboronicacidpinacolesterhydrochloride

Suppliers and Price of Imidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of Imidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one

Chemical Property:

PSA：63.31000
LogP:0.98310
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:186.05416083
Heavy Atom Count:14
Complexity:257

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(N=C1)N3C=NC=C3C(=O)N2

Technology Process of Imidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one

There total 4 articles about Imidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 240815-48-9
N-(2-chloro-3-pyridinyl)-1H-imidazole-4-carboxamide

: 240815-49-0
imidazo[1,5-a]-pyrido[2,3-e]pyrazin-6(5H)-one

Guidance literature:: With potassium carbonate; In N,N-dimethyl acetamide; for 6h; Heating;
DOI:10.1016/S0040-4039(01)00698-0

Reference yield:

: 240815-48-9
N-(2-Chloro-3-pyridinyl)-1H-imidazole-4-carboxamide

: 240815-49-0
imidazo[1,5-a]-pyrido[2,3-e]pyrazin-6(5H)-one

Guidance literature:: With potassium carbonate; In ISOPROPYLAMIDE; for 6h; Heating / reflux;

Reference yield:

: 6298-19-7
2-chloro-3-aminopyridine

: 240815-49-0
imidazo[1,5-a]-pyrido[2,3-e]pyrazin-6(5H)-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium bis(trimethylsilyl)amide / tetrahydrofuran / 1 h / -10 °C

1.2: 40 percent / tetrahydrofuran / 2 h / 20 °C

2.1: 83 percent / potassium carbonate / N,N-dimethyl-acetamide / 6 h / Heating

With sodium hexamethyldisilazane; potassium carbonate; In tetrahydrofuran; N,N-dimethyl acetamide;
DOI:10.1021/jm030217e