7-(3-aminomethyl-4-fluoromethoxyimino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid methanesulfonate

Base Information

Chemical Name:7-(3-aminomethyl-4-fluoromethoxyimino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid methanesulfonate
CAS No.:1356948-26-9
Molecular Formula:CH₄O₃S*C₂₁H₁₇F₄N₅O₄
Molecular Weight:575.498
Hs Code.:

7-(3-aminomethyl-4-fluoromethoxyimino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid methanesulfonate

Synonyms:7-(3-aminomethyl-4-fluoromethoxyimino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid methanesulfonate

Suppliers and Price of 7-(3-aminomethyl-4-fluoromethoxyimino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7-(3-aminomethyl-4-fluoromethoxyimino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid methanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7-(3-aminomethyl-4-fluoromethoxyimino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid methanesulfonate

There total 3 articles about 7-(3-aminomethyl-4-fluoromethoxyimino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.4%

: 75-75-2,98527-29-8
methanesulfonic acid

: 1356857-73-2
7-(3-benzylideneaminomethyl-4-fluoromethoxyimino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid

: 1356948-26-9
7-(3-aminomethyl-4-fluoromethoxyimino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid methanesulfonate

Guidance literature:: In ethanol; water; at 20 ℃; for 16h;
DOI:10.1016/j.ejmech.2011.10.048

Reference yield:

: 3-aminomethyl-4-(fluoromethoxyimino)pyrrolidine dimethanesulfonate

: 1356948-26-9
7-(3-aminomethyl-4-fluoromethoxyimino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid methanesulfonate

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / acetonitrile / 2 h / 20 °C

2: acetonitrile / 12 h / 20 °C

3: ethanol; water / 16 h / 20 °C

With triethylamine; In ethanol; water; acetonitrile;
DOI:10.1016/j.ejmech.2011.10.048

Reference yield:

: C₁₃H₁₆FN₃O

: 1356948-26-9
7-(3-aminomethyl-4-fluoromethoxyimino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid methanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 12 h / 20 °C

2: ethanol; water / 16 h / 20 °C

In ethanol; water; acetonitrile;
DOI:10.1016/j.ejmech.2011.10.048