N-[2-(1-benzenesulfonyl-1H-imidazol-4-yl)-ethyl]-N-prop-2-ynyl-benzenesulfonamide

Base Information

Chemical Name:N-[2-(1-benzenesulfonyl-1H-imidazol-4-yl)-ethyl]-N-prop-2-ynyl-benzenesulfonamide
CAS No.:331731-80-7
Molecular Formula:C₂₀H₁₉N₃O₄S₂
Molecular Weight:429.521
Hs Code.:

<i>N</i>-[2-(1-benzenesulfonyl-1<i>H</i>-imidazol-4-yl)-ethyl]-<i>N</i>-prop-2-ynyl-benzenesulfonamide

Synonyms:N-[2-(1-benzenesulfonyl-1H-imidazol-4-yl)-ethyl]-N-prop-2-ynyl-benzenesulfonamide

Suppliers and Price of N-[2-(1-benzenesulfonyl-1H-imidazol-4-yl)-ethyl]-N-prop-2-ynyl-benzenesulfonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[2-(1-benzenesulfonyl-1H-imidazol-4-yl)-ethyl]-N-prop-2-ynyl-benzenesulfonamide

Chemical Property:

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Technology Process of N-[2-(1-benzenesulfonyl-1H-imidazol-4-yl)-ethyl]-N-prop-2-ynyl-benzenesulfonamide

There total 3 articles about N-[2-(1-benzenesulfonyl-1H-imidazol-4-yl)-ethyl]-N-prop-2-ynyl-benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 106-96-7
propargyl bromide

: 195053-77-1
N^α,N^τ-di-benzenesulfonyl histamine

: 331731-80-7
N-[2-(1-benzenesulfonyl-1H-imidazol-4-yl)-ethyl]-N-prop-2-ynyl-benzenesulfonamide

Guidance literature:: N^α,N^τ-di-benzenesulfonyl histamine; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

propargyl bromide; In N,N-dimethyl-formamide; at 20 ℃; for 2h;
DOI:10.1016/S0040-4020(00)01030-9

Reference yield:

: 56-92-8
histamine dichloride

: 331731-80-7
N-[2-(1-benzenesulfonyl-1H-imidazol-4-yl)-ethyl]-N-prop-2-ynyl-benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium bicarbonate / tetrahydrofuran; H₂O / 24 h / 20 °C

2.1: NaH / dimethylformamide / 0.5 h / 20 °C

2.2: dimethylformamide / 2 h / 20 °C

With sodium hydride; sodium hydrogencarbonate; In tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(00)01030-9

Reference yield:

: 98-09-9
benzenesulfonyl chloride

: 331731-80-7
N-[2-(1-benzenesulfonyl-1H-imidazol-4-yl)-ethyl]-N-prop-2-ynyl-benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium bicarbonate / tetrahydrofuran; H₂O / 24 h / 20 °C

2.1: NaH / dimethylformamide / 0.5 h / 20 °C

2.2: dimethylformamide / 2 h / 20 °C

With sodium hydride; sodium hydrogencarbonate; In tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(00)01030-9