9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one

Base Information

Chemical Name:9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one
CAS No.:1338543-46-6
Molecular Formula:C₁₃H₁₀BrNO₂S
Molecular Weight:324.198
Hs Code.:
Mol file:1338543-46-6.mol

Synonyms:9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one

Suppliers and Price of 9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemicals and raw materials
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Total 4 raw suppliers

Chemical Property of 9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
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Technology Process of 9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one

There total 7 articles about 9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1338543-45-5
8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one

: 1338543-46-6
9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one

Guidance literature:: With N-Bromosuccinimide; acetic acid; In dichloromethane; at 20 ℃;
DOI:10.1016/j.ejmech.2018.11.007

Reference yield:

: 7311-64-0
3-bromothiophene-2-carboxylic acid

: 1338543-46-6
9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one

Guidance literature:: Multi-step reaction with 5 steps

1: thionyl chloride; N,N-dimethyl-formamide / 2 h / Reflux

2: triethylamine / dichloromethane / 2 h / 20 °C

3: dmap / dichloromethane / 20 °C

4: potassium acetate; bis(tri-t-butylphosphine)palladium⁽⁰⁾ / N,N-dimethyl acetamide / 2 h / Heating; Inert atmosphere

5: acetic acid; N-Bromosuccinimide / dichloromethane / 20 °C

With dmap; N-Bromosuccinimide; thionyl chloride; bis(tri-t-butylphosphine)palladium⁽⁰⁾; potassium acetate; acetic acid; triethylamine; N,N-dimethyl-formamide; In dichloromethane; N,N-dimethyl acetamide;
DOI:10.1016/j.ejmech.2018.11.007

Reference yield:

: 1275804-56-2
3-bromo-N-(4-methoxy-2-methylphenyl)thiophene-2-carboxamide

: 1338543-46-6
9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: dmap / dichloromethane / 20 °C

2: potassium acetate; bis(tri-t-butylphosphine)palladium⁽⁰⁾ / N,N-dimethyl acetamide / 2 h / Heating; Inert atmosphere

3: acetic acid; N-Bromosuccinimide / dichloromethane / 20 °C

With dmap; N-Bromosuccinimide; bis(tri-t-butylphosphine)palladium⁽⁰⁾; potassium acetate; acetic acid; In dichloromethane; N,N-dimethyl acetamide;
DOI:10.1016/j.ejmech.2018.11.007