substance P (6-11)

Base Information

Chemical Name:substance P (6-11)
CAS No.:51165-07-2
Molecular Formula:C36H52 N8 O7 S
Molecular Weight:740.924
Hs Code.:
DSSTox Substance ID:DTXSID20199187
Nikkaji Number:J274.730H
Wikidata:Q76010347
ChEMBL ID:CHEMBL281816
Mol file:51165-07-2.mol

Synonyms:1-dearginyl-2,4-deprolyl-3-delysyl-5-deglutamine-substance P;1-des-Arg-2,4-des-Pro-3-des-Lys-5-des-Gln-substance P;pGlu SPH;sendide;SP(6-11);SP6-11(C-terminal);substance P (6-11);substance P hexapeptide;substance P, dearginyl(1)-deprolyl(2,4)-delysyl(3)-deglutamine(5)-

Suppliers and Price of substance P (6-11)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Biorbyt Ltd
Substance P (6-11) > 95%
5 mg
$ 552.50

Biorbyt Ltd
Substance P (6-11) > 95%
1 mg
$ 287.30

Biorbyt Ltd
Substance P (6-11) > 95%
10 mg
$ 708.90

American Custom Chemicals Corporation
SUBSTANCE P(6-11) 95.00%
1MG
$ 617.93

Total 10 raw suppliers

Chemical Property of substance P (6-11)

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:1198.9°C at 760 mmHg
Flash Point:678.9°C
PSA：283.00000
Density:1.24g/cm³
LogP:3.45990
Storage Temp.:-15°C
XLogP3:0.7
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:23
Exact Mass:740.36796720
Heavy Atom Count:52
Complexity:1190

Purity/Quality:

99%, ^*data from raw suppliers

Substance P (6-11) > 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)N
Isomeric SMILES:CC(C)C[C@@H](C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)CNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CCC(=O)N)N

Technology Process of substance P (6-11)

There total 20 articles about substance P (6-11) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 64699-01-0
t-butyloxycarbonyl-glutamyl-phenylalanyl-phenylalanyl-glycyl-leucyl-methionine amide

: 51165-07-2,78081-72-8
glutamyl-phenylalanyl-phenylalanyl-glycyl-leucyl-methionine amide

Guidance literature:: With hydrogenchloride; acetic acid; for 0.5h;

Reference yield:

: 13139-15-6,53296-34-7
N-tert-butoxycarbonyl-L-leucine

: 51165-07-2,78081-72-8
glutamyl-phenylalanyl-phenylalanyl-glycyl-leucyl-methionine amide

Guidance literature:: Multi-step reaction with 4 steps

1: 93.6 percent / NMM, IBCF / dimethylformamide / -20 °C

2: TFA, anisole / CH₂Cl₂ / 1 h / 0 °C

3: 90 percent / HCl, IBCF, NMM / dimethylformamide / -15 °C

4: TFA, anisole / CH₂Cl₂ / 1 h / 0 °C

With 4-methyl-morpholine; hydrogenchloride; methoxybenzene; trifluoroacetic acid; isobutyl chloroformate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/0223-5234(88)90006-2

Reference yield:

: 2280-68-4
N-tert-butoxycarbonyl-L-leucyl-L-methioninamide

: 51165-07-2,78081-72-8
glutamyl-phenylalanyl-phenylalanyl-glycyl-leucyl-methionine amide

Guidance literature:: Multi-step reaction with 3 steps

1: TFA, anisole / CH₂Cl₂ / 1 h / 0 °C

2: 90 percent / HCl, IBCF, NMM / dimethylformamide / -15 °C

3: TFA, anisole / CH₂Cl₂ / 1 h / 0 °C

With 4-methyl-morpholine; hydrogenchloride; methoxybenzene; trifluoroacetic acid; isobutyl chloroformate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/0223-5234(88)90006-2