Technology Process of C18H15Cl2NO2
There total 5 articles about C18H15Cl2NO2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
pyridine; dihydrogen peroxide;
In
dichloromethane; water;
at 0 - 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1016/j.bmcl.2012.08.114
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: triethylamine / dichloromethane / 1 h / 0 °C
2.1: lithium bromide / acetonitrile / Inert atmosphere; Reflux
3.1: sodium ethanolate / ethanol; N,N-dimethyl-formamide / 0.5 h
3.2: 24 h / Reflux
4.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere
5.1: pyridine; dihydrogen peroxide / dichloromethane; water / 2 h / 0 - 20 °C / Inert atmosphere
With
pyridine; n-butyllithium; dihydrogen peroxide; sodium ethanolate; triethylamine; diisopropylamine; lithium bromide;
In
tetrahydrofuran; ethanol; hexane; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.bmcl.2012.08.114
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium ethanolate / ethanol; N,N-dimethyl-formamide / 0.5 h
1.2: 24 h / Reflux
2.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere
3.1: pyridine; dihydrogen peroxide / dichloromethane; water / 2 h / 0 - 20 °C / Inert atmosphere
With
pyridine; n-butyllithium; dihydrogen peroxide; sodium ethanolate; diisopropylamine;
In
tetrahydrofuran; ethanol; hexane; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.08.114
